2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

Base Information

Chemical Name:2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate
CAS No.:1181809-34-6
Molecular Formula:CF₃O₃S*C₁₆H₁₆ClFIN₂O₂
Molecular Weight:598.742
Hs Code.:

Synonyms:2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

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Chemical Property of 2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

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Technology Process of 2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

There total 1 articles about 2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1181809-22-2
6-chloro-2-(2-fluoro-4-iodophenylamino)-5-methylnicotinic acid ethyl ester

: 333-27-7
methyl trifluoromethanesulfonate

: 1181809-34-6
2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

Guidance literature:: In chlorobenzene; at 20 - 90 ℃;

Reference yield:

: 1181809-34-6
2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate

: 1181809-21-1
2-(2-fluoro-4-iodophenylamino)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Guidance literature:: 2-chloro-6-(2-fluoro-4-iodo-phenylamino)-5-ethoxycarbonyl-1,3-dimethyl-pyridinium trifluoromethanesulfonate; With sodium hydroxide; In IMS (industrial methylated spirit); at 50 ℃; for 7.16667h;

With hydrogenchloride; water; In IMS (industrial methylated spirit); acetonitrile; at 50 ℃; for 3h;