N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Base Information

Chemical Name:N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide
CAS No.:1341219-95-1
Molecular Formula:C₃₀H₄₄BrNO₈Si
Molecular Weight:654.671
Hs Code.:

Synonyms:N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Suppliers and Price of N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

There total 5 articles about N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 22118-09-8
2-bromoacetyl chloride

: 1341219-92-8
N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)-3-allyl-4-methoxy-2,5-dimethoxymethoxyaniline

: 1341219-95-1
N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 0.333333h;
DOI:10.1021/jo201495w

Reference yield:

: 129742-36-5
(4-((tert-butyldimethylsilyl)oxy)-2-methoxybenzaldehyde)

: 1341219-95-1
N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / dichloromethane / 0.17 h / 20 °C

2: sodium tris(acetoxy)borohydride / dichloromethane / 0.33 h / 0 - 20 °C

3: triethylamine / dichloromethane / 0.33 h / 0 - 20 °C

With sodium tris(acetoxy)borohydride; acetic acid; triethylamine; In dichloromethane;
DOI:10.1021/jo201495w

Reference yield:

: 18278-34-7
4-hydroxy-2-methoxybenzaldehyde

: 1341219-95-1
N-(3-allyl-4-methoxy-2,5-dimethoxymethoxyphenyl)-N-(4-tert-butyldimethylsiloxy-2-methoxybenzyl)bromoacetamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

2: acetic acid / dichloromethane / 0.17 h / 20 °C

3: sodium tris(acetoxy)borohydride / dichloromethane / 0.33 h / 0 - 20 °C

4: triethylamine / dichloromethane / 0.33 h / 0 - 20 °C

With 1H-imidazole; sodium tris(acetoxy)borohydride; acetic acid; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo201495w