3-Methoxy-10H-phenothiazine

Base Information Edit

Chemical Name:3-Methoxy-10H-phenothiazine
CAS No.:1771-19-3
Molecular Formula:C13H11 N O S
Molecular Weight:229.302
Hs Code.:2934300000
European Community (EC) Number:217-196-0
DSSTox Substance ID:DTXSID80170250
Nikkaji Number:J121.698H
Wikidata:Q83040149
Pharos Ligand ID:W2X14W1YP1QM
ChEMBL ID:CHEMBL1331821
Mol file:1771-19-3.mol

Synonyms:3-Methoxy-10H-phenothiazine;1771-19-3;Phenothiazine, 3-methoxy-;10H-PHENOTHIAZINE, 3-METHOXY-;EINECS 217-196-0;SR-01000025134;SR-01000025134-4;3-Methoxyphenothiazine;starbld0003423;Enamine_005797;Oprea1_686245;cid_74491;MLS001005666;SCHEMBL4080414;3-Methoxy-10H-phenothiazine #;CHEMBL1331821;BDBM65843;DTXSID80170250;HMS1410H11;HMS2707K17;AKOS034450710;IDI1_008032;NCGC00245981-01;SMR000348948;CS-0303049;10H-Dibenzo[b,E]-1,4-thiazine, 3-methoxy-;SR-01000025134-1;SR-01000025134-3;Z56754478

Suppliers and Price of 3-Methoxy-10H-phenothiazine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methoxy-10H-phenothiazine
2.5g
$ 430.00

Total 6 raw suppliers

Chemical Property of 3-Methoxy-10H-phenothiazine Edit

Chemical Property:

Vapor Pressure:6.16E-07mmHg at 25°C
Boiling Point:410.1°Cat760mmHg
Flash Point:201.9°C
PSA：46.56000
Density:1.235g/cm³
LogP:4.04140
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:229.05613515
Heavy Atom Count:16
Complexity:248

Purity/Quality:

99% ^*data from raw suppliers

3-Methoxy-10H-phenothiazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)NC3=CC=CC=C3S2
Uses 3-Methoxy-10H-phenothiazine is used in the synthesis of 10-Dechlorovancomycin (D226740), which is an impurity of Vancomycin (V096500, HCl salt) which is an amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Vancomycin inhibits bacterial cell wall synthesis by binding to peptidoglycan.

Technology Process of 3-Methoxy-10H-phenothiazine

There total 23 articles about 3-Methoxy-10H-phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 95-16-9
1,3-Benzothiazole

: 4897-68-1
2-iodo-4-methoxybromobenzene

: 1771-19-3
3-methoxy-10H-phenothiazine

Guidance literature:: With copper(ll) sulfate pentahydrate; N-(cyclopentyloxy)-1H-pyrrole-2-carboxamide; sodium hydroxide; at 80 ℃; for 14h; Sealed tube;

Reference yield: 72.0%

: 2732-80-1
2-bromo-1-chloro-4-methoxybenzene

: 137-07-5
2-amino-benzenethiol

: 1771-19-3
3-methoxy-10H-phenothiazine

Guidance literature:: With copper(l) iodide; potassium carbonate; In dimethyl sulfoxide; at 120 ℃; for 48h; regioselective reaction; Inert atmosphere;
DOI:10.1039/c2cc30814b

Reference yield: 65.0%

: 2942-13-4
6-methoxy-1,3-benzothiazole

: 583-55-1
1-Bromo-2-iodobenzene

: 1771-19-3
3-methoxy-10H-phenothiazine

Guidance literature:: With N-(benzyloxy)-1H-pyrrole-2-carboxamide; copper(II) acetate monohydrate; sodium hydroxide; at 90 ℃; for 12h; Sealed tube; Inert atmosphere; Green chemistry;
DOI:10.1002/ejoc.201500667