bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

Base Information

Chemical Name:bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate
CAS No.:1337533-20-6
Molecular Formula:C₃₃H₃₂F₂IN₃O₆
Molecular Weight:731.535
Hs Code.:

Synonyms:bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

There total 2 articles about bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1337532-96-3
3-(1-[(2,5-difluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-amine

: 1337533-20-6
bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

Guidance literature:: With triethylamine; dmap; In dichloromethane; at 20 ℃; for 17h; Inert atmosphere;

Reference yield:

: 1337531-46-0
3-{1-[(2,5-difluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}furo[3,2-c]pyridin-4-amine

: 1337533-20-6
bis(1,1-dimethylethyl) (3-(1-[(2,5-difluorophenyI)acetyl]-2,3-dihydro-1H-indol-5-yl)-7-iodofuro[3,2-c]pyridin-4-yI)imidodicarbonate

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / N,N-dimethyl-formamide / 18 h / -40 - 20 °C

2: triethylamine / dmap / dichloromethane / 17 h / 20 °C / Inert atmosphere

With N-iodo-succinimide; triethylamine; dmap; In dichloromethane; N,N-dimethyl-formamide;