Arginyl-glycyl-aspartic acid

Base Information

Chemical Name:Arginyl-glycyl-aspartic acid
CAS No.:99896-85-2
Molecular Formula:C12H22N6O6
Molecular Weight:346.343
Hs Code.:2925290090
UNII:78VO7F77PN
DSSTox Substance ID:DTXSID30912420
Nikkaji Number:J475.976A
Wikipedia:Arginylglycylaspartic_acid
Wikidata:Q4068819,Q105122814
Metabolomics Workbench ID:79599
ChEMBL ID:CHEMBL313763
Mol file:99896-85-2.mol

Synonyms:Arg-Gly-Asp;arginyl-glycyl-aspartic acid;F-336;RGD peptide;RGD tripeptide

Suppliers and Price of Arginyl-glycyl-aspartic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Arg-Gly-Asp
50mg
$ 305.00

Sigma-Aldrich
Arg-Gly-Asp ≥97% (TLC)
10mg
$ 150.00

Sigma-Aldrich
Arg-Gly-Asp ≥97% (TLC)
1mg
$ 28.60

Sigma-Aldrich
Arg-Gly-Asp ≥97% (TLC)
5mg
$ 83.50

CSNpharm
Arg-Gly-Asp
5mg
$ 60.00

Crysdot
Arg-Gly-Asp 95+%
100mg
$ 490.00

Chem-Impex
H-Arg-Gly-Asp-OH,98%(HPLC) 98%(HPLC)
25MG
$ 100.80

Chem-Impex
H-Arg-Gly-Asp-OH,98%(HPLC) 98%(HPLC)
250MG
$ 716.80

Chem-Impex
H-Arg-Gly-Asp-OH,98%(HPLC) 98%(HPLC)
100MG
$ 347.20

Chemenu
Arg-Gly-Asp 95%
100mg
$ 458.00

Total 52 raw suppliers

Chemical Property of Arginyl-glycyl-aspartic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:153-155℃ (ethyl ether )
Refractive Index:1.671
Boiling Point:597.205°C at 760 mmHg
PKA:2.85±0.10(Predicted)
Flash Point:314.979°C
PSA：220.72000
Density:1.61 g/cm³
LogP:-0.58970
Storage Temp.:−20°C
Solubility.:Soluble in 0.1N acetic acid at 20mg/ml
XLogP3:-6
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:346.16008244
Heavy Atom Count:24
Complexity:504

Purity/Quality:

99%, ^*data from raw suppliers

Arg-Gly-Asp ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)O)N)CN=C(N)N
Isomeric SMILES:C(C[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N)CN=C(N)N
Recent ClinicalTrials:The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect
Uses Arg-Gly-Asp has been used:to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogelin adhesion assayin inhibition assay to confirm the β1-integrin-dependency of cell adhesionin textile fabrication and RGD textile functionalizationto engineer a population of human dermal fibroblasts with impaired migrationto modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)in the cell culture of human mammary epithelial cells

Technology Process of Arginyl-glycyl-aspartic acid

There total 6 articles about Arginyl-glycyl-aspartic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: Arg(Pbf)-Gly-Asp(OtBu)

: 99896-85-2,119865-10-0
Arg-Gly-Asp

Guidance literature:: With methanol; triethylsilane; water; trifluoroacetic acid; at 20 ℃; for 2h;
DOI:10.1002/cmdc.201800704

Reference yield: 54.0%

: 4685-12-5
glycyl-L-aspartic acid

: 108787-79-7
N^α,N^G,N^G'-tri-Boc-L-arginine N-hydroxysuccinimide ester

: 99896-85-2,119865-10-0
Arg-Gly-Asp

Guidance literature:: glycyl-L-aspartic acid; N^α,N^G,N^G'-tri-Boc-L-arginine N-hydroxysuccinimide ester; With 4-methyl-morpholine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

With trifluoroacetic acid; In chloroform;
DOI:10.1007/BF02464250