1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

Base Information

• Chemical Name: 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine
• CAS No.: 575472-08-1
• Molecular Formula: C₃₁H₅₃NO₇SSi₂
• Molecular Weight: 640.001

Synonyms:1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

Chemical Property of 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

There total 7 articles about 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

di-tert-butyl dicarbonate (24424-99-5) + 1-O-benzyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine (575472-07-0) → 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine (575472-08-1)

Guidance literature:

In pyridine; at 20 ℃; for 24h;

DOI:10.1016/S0008-6215(03)00007-7

Reference yield:

L-sorbose (35673-97-3) → 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine (575472-08-1)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 55 percent / H₂SO₄

2.1: 96 percent / NaH / dimethylformamide

3.1: TFA / H₂O

3.2: 78 percent / HCl / H₂O / 48 h / 50 °C

4.1: 85 percent / imidazole / dimethylformamide / 20 °C

5.1: 95 percent / pyridine / 24 h / 20 °C

With 1H-imidazole; sulfuric acid; sodium hydride; trifluoroacetic acid; In pyridine; water; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(03)00007-7

Reference yield:

benzyl bromide (100-39-0) → 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine (575472-08-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 96 percent / NaH / dimethylformamide

2.1: TFA / H₂O

2.2: 78 percent / HCl / H₂O / 48 h / 50 °C

3.1: 85 percent / imidazole / dimethylformamide / 20 °C

4.1: 95 percent / pyridine / 24 h / 20 °C

With 1H-imidazole; sodium hydride; trifluoroacetic acid; In pyridine; water; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(03)00007-7

upstream raw materials:

di-tert-butyl dicarbonate

1-O-benzyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

L-sorbose

benzyl bromide

Downstream raw materials:

1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-carbonyl-α-L-sorbofuranosylamine

1-O-benzyl-2-N,3-O-carbonyl-α-L-sorbofuranosylamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 575472-08-1 1-O-benzyl-2-N-tert-butoxycarbonyl-4,6-di-O-tert-butyldimethylsilyl-2-N,3-O-thiocarbonyl-α-L-sorbofuranosylamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send