2,3,5,6-tetrafluoro-4-mesitylpyridine

Base Information

• Chemical Name: 2,3,5,6-tetrafluoro-4-mesitylpyridine
• CAS No.: 1363958-69-3
• Molecular Formula: C₁₄H₁₁F₄N
• Molecular Weight: 269.242
• Mol file: 1363958-69-3.mol

Synonyms:2,3,5,6-tetrafluoro-4-mesitylpyridine

Chemical Property of 2,3,5,6-tetrafluoro-4-mesitylpyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,5,6-tetrafluoro-4-mesitylpyridine

There total 2 articles about 2,3,5,6-tetrafluoro-4-mesitylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2,3,5,6-tetrafluoropyridine (2875-18-5) + 2,4,6-trimethylphenyl trifluoromethanesulfonate (125261-32-7) → 2,3,5,6-tetrafluoro-4-mesitylpyridine (1363958-69-3)

Guidance literature:

With palladium diacetate; potassium carbonate; ruphos; In 1,4-dioxane; at 100 ℃; for 17h; Inert atmosphere; Microwave irradiation;

DOI:10.1039/c2ob06840k

Reference yield:

Mesitol (527-60-6) → 2,3,5,6-tetrafluoro-4-mesitylpyridine (1363958-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

2: palladium diacetate; potassium carbonate; ruphos / 1,4-dioxane / 17 h / 100 °C / Inert atmosphere; Microwave irradiation

With pyridine; palladium diacetate; potassium carbonate; ruphos; In 1,4-dioxane; dichloromethane;

DOI:10.1039/c2ob06840k

upstream raw materials:

2,3,5,6-tetrafluoropyridine

2,4,6-trimethylphenyl trifluoromethanesulfonate

Mesitol

Refernces