d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene

Base Information

• Chemical Name: d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene
• CAS No.: 959786-30-2
• Molecular Formula: C₁₆H₁₈O₂
• Molecular Weight: 245.294
• Mol file: 959786-30-2.mol

Synonyms:d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene

Chemical Property of d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene

There total 4 articles about d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

[2H3]methyl methanesulfonate (91419-94-2) + 2-(4-benzyloxyphenyl)ethanol (61439-59-6) → d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene (959786-30-2)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield:

Methyl 4-hydroxyphenylacetate (14199-15-6) → d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene (959786-30-2)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 0 - 60 °C

2: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

3: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

With lithium aluminium tetrahydride; sodium hydride; potassium carbonate; In diethyl ether; N,N-dimethyl-formamide;

Reference yield:

(4-benzyloxy-phenyl)-acetic acid methyl ester (68641-16-7) → d3-1-benzyloxy-4-(2-methoxy-ethyl)-benzene (959786-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / diethyl ether / 0 - 20 °C

2: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C

With lithium aluminium tetrahydride; sodium hydride; In diethyl ether; N,N-dimethyl-formamide;

upstream raw materials:

[²H₃]methyl methanesulfonate

2-(4-benzyloxyphenyl)ethanol

Methyl 4-hydroxyphenylacetate

(4-benzyloxy-phenyl)-acetic acid methyl ester

Downstream raw materials:

d3-4-(2-methoxy-ethyl)-phenol

d3-2-[4-(2-methoxy-ethyl)phenoxymethyl]-oxirane

Refernces