L-gamma-Glutamylhydrazide

Base Information

• Chemical Name: L-gamma-Glutamylhydrazide
• CAS No.: 1820-73-1
• Molecular Formula: C5H11 N3 O3
• Molecular Weight: 161.161
• Hs Code.: 2928000090
• European Community (EC) Number: 217-337-6
• UNII: FAJ12751NB
• DSSTox Substance ID: DTXSID201309271
• Nikkaji Number: J199.638J
• Wikidata: Q27277889
• Mol file: 1820-73-1.mol

Synonyms:gamma-glutamyl hydrazide;gamma-glutamylhydrazide;glutamic acid-gamma-semihydrazide;L-glutamic acid-gamma-hydrazide;L-glutamic acid-gamma-hydrazide, (DL)-isomer;L-glutamic acid-gamma-hydrazide, (L)-isomer, sodium salt

Chemical Property of L-gamma-Glutamylhydrazide

Chemical Property:

• Vapor Pressure: 1.85E-10mmHg at 25°C
• Melting Point: 164-165℃ C
• Boiling Point: 478.1°C at 760 mmHg
• PKA: 2.18±0.10(Predicted)
• Flash Point: 243°C
• PSA: 118.44000
• Density: 1.35g/cm³
• LogP: -0.04010
• Storage Temp.: −20°C
• Sensitive.: Light Sensitive
• Water Solubility.: Soluble in water
• XLogP3: -4.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 161.08004122
• Heavy Atom Count: 11
• Complexity: 159

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-GLUTAMIC ACID GAMMA-HYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)NN)C(C(=O)O)N
• Isomeric SMILES: C(CC(=O)NN)[C@@H](C(=O)O)N
• Uses: A modified amino acid; also known as H-L-Glu(NHNH2)-OH. A glutamine antagonist

Technology Process of L-gamma-Glutamylhydrazide

There total 5 articles about L-gamma-Glutamylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.6%

L-Pyroglutamic acid (98-79-3) → glutamic acid γ-hydrazide (1820-73-1)

Guidance literature:

With hydrazine; In ethanol; water; Heating;

DOI:10.1246/bcsj.54.2219

Reference yield:

L-glutamic acid 5-methyl ester (1499-55-4) → glutamic acid γ-hydrazide (1820-73-1)

Guidance literature:

With water; hydrazine hydrate;

Reference yield:

(S)-2-Amino-pentanedioic acid 5-ethyl ester (1119-33-1) → glutamic acid γ-hydrazide (1820-73-1)

Guidance literature:

With water; hydrazine hydrate;

upstream raw materials:

L-glutamic acid 5-methyl ester

(S)-2-Amino-pentanedioic acid 5-ethyl ester

L-Pyroglutamic acid

L-glutamic acid

Downstream raw materials:

L-glutamine

L-glutamic acid

phosphoric acid

L-Pyroglutamic acid