1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane

Base Information

• Chemical Name: 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane
• CAS No.: 1242410-89-4
• Molecular Formula: C₂₀H₃₂N₄
• Molecular Weight: 328.501
• Mol file: 1242410-89-4.mol

Synonyms:1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane

Chemical Property of 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane

Chemical Property:

Purity/Quality:

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Technology Process of 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane

There total 1 articles about 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N,N-dimethylammonium chloride (506-59-2) + 2,2'-(cyclohexane-1,1-diyl)bis(1H-pyrrole) (35303-46-9) → 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane (1242410-89-4)

Guidance literature:

In ethanol; at 0 - 20 ℃;

DOI:10.1021/ol101598e

Reference yield: 93.0%

1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane (1242410-89-4) + methyl iodide (74-88-4) → C22H38N4(2+)*2I(1-)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1039/c5dt00430f

Reference yield: 32.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + 1,1′-bis[2-(N,N-dimethylaminomethyl)-5-pyrrolyl]cyclohexane (1242410-89-4) → 1,1′-bis[2-(3,5-dimethylpyrazolylmethyl)-5-pyrrolyl]cyclohexane

Guidance literature:

In 5,5-dimethyl-1,3-cyclohexadiene; at 140 ℃; for 24h; Reflux;

DOI:10.1039/c5dt00430f

upstream raw materials:

formaldehyd

N,N-dimethylammonium chloride

2,2'-(cyclohexane-1,1-diyl)bis(1H-pyrrole)