2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Base Information

Chemical Name:2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene
CAS No.:254744-55-3
Molecular Formula:C₂₁H₂₇BrN₂O₃
Molecular Weight:435.361
Hs Code.:

Synonyms:2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Suppliers and Price of 2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(4-Bromo-3-(1,3-dioxolan-2-yl)benzyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one 95+%
5g
$ 2679.00

Crysdot
3-(4-Bromo-3-(1,3-dioxolan-2-yl)benzyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one 95+%
1g
$ 892.00

Chemenu
3-(4-Bromo-3-(1,3-dioxolan-2-yl)benzyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one 95%
1g
$ 842.00

AK Scientific
3-(4-Bromo-3-[1,3]Dioxolan-2-Yl-Benzyl)-2-Butyl-1,3-Diaza-Spiro[4.4]Non-1-En-4-One
250mg
$ 507.20

Total 3 raw suppliers

Chemical Property of 2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Chemical Property:

Boiling Point:533.3±60.0 °C(Predicted)
Density:1.45±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Bromo-3-(1,3-dioxolan-2-yl)benzyl)-2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

There total 5 articles about 2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride

: 254744-55-3
2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Guidance literature:: In N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 138402-05-8
2-butyl-1,3-diaza-spiro[4.4]non-1-en-4one

: 254744-54-2
2-[(2'-bromo-5'-bromomethyl)phenyl]-1,3-dioxolane

: 254744-55-3
2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Guidance literature:: 2-butyl-1,3-diaza-spiro[4.4]non-1-en-4one; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.25h;

2-[(2'-bromo-5'-bromomethyl)phenyl]-1,3-dioxolane; In N,N-dimethyl-formamide; for 14h; Further stages.;
DOI:10.1021/jm020138n

Reference yield:

: 160313-48-4
2-[(2'-bromo-5'-hydroxymethyl)phenyl]-1,3-dioxolane

: 254744-55-3
2-(1,3-Dioxolan-2-yl)-4-[(2-n-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]bromobenzene

Guidance literature:: Multi-step reaction with 2 steps

1.1: 31.1 g / carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 2 h / 0 °C

2.1: sodium hydride / dimethylformamide / 0.25 h / 0 - 20 °C

2.2: 42.7 g / dimethylformamide / 14 h

With carbon tetrabromide; sodium hydride; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm020138n