(5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

Base Information

• Chemical Name: (5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine
• CAS No.: 331822-77-6
• Molecular Formula: C₂₇H₃₇N₅O₃Si
• Molecular Weight: 507.708

Synonyms:(5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

Chemical Property of (5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

There total 1 articles about (5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-butyl(triphenyl)phosphonium bromide (1779-51-7) + 5'-aldehyde-2'-deoxy-6-N-benzoyl-3'-O-tertbutyldimethylsilyl adenosine (167700-45-0) → (5'Z)-N6-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine (331822-77-6) + (5'E)-N6-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

Guidance literature:

n-butyl(triphenyl)phosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; for 1h; Heating;

5'-aldehyde-2'-deoxy-6-N-benzoyl-3'-O-tertbutyldimethylsilyl adenosine; In tetrahydrofuran; at -78 - 0 ℃; for 5h;

DOI:10.1002/1522-2675(20010131)84:1<87::AID-HLCA87>3.0.CO;2-1

Reference yield: 76.0%

(5'Z)-N6-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine (331822-77-6) → N6-benzoyl-3'-O-[(tert-butyl)dimethylsilyl]-5'-butylidene-2',5'-dideoxy-7,8-dihydroadenosine

Guidance literature:

(5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine; With borane-THF; In tetrahydrofuran; at -40 - -20 ℃; for 2.16667h;

With Oxone; sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1002/1522-2675(20010131)84:1<87::AID-HLCA87>3.0.CO;2-1

Reference yield: 13.0%

(5'Z)-N6-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine (331822-77-6) → (5'R,6'S)-N6-benzoyl-5'-C-butyl-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxy-5',6'-epoxyadenosine + (5'S,6'R)-N6-benzoyl-5'-C-butyl-3'-O-[(tert-butyl)dimethylsilyl]-2,5'-dideoxy-5',6'-epoxyadenosine

Guidance literature:

With 3,3-dimethyldioxirane; In dichloromethane; acetone; at 0 - 20 ℃; for 26h;

DOI:10.1002/1522-2675(20010131)84:1<87::AID-HLCA87>3.0.CO;2-1

upstream raw materials:

n-butyl(triphenyl)phosphonium bromide

5'-aldehyde-2'-deoxy-6-N-benzoyl-3'-O-tertbutyldimethylsilyl adenosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 331822-77-6 (5'Z)-N⁶-benzoyl-5'-C-butylidene-3'-O-[(tert-butyl)dimethylsilyl]-2',5'-dideoxyadenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send