Technology Process of 2-bromo-6-hydroxy-3-phenylinden-1-one
There total 6 articles about 2-bromo-6-hydroxy-3-phenylinden-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; lithium hydroxide;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 5h;
DOI:10.1246/cl.2008.1068
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydroxide / ethanol; water / 27.5 h / 10 - 20 °C
2: trifluoroacetic acid / 24 h / 80 °C
3: pyridine / dichloromethane / 8 h / 0 - 20 °C
4: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 2.5 h / Reflux; Irradiation
5: potassium carbonate; methanol / 2 h / 20 °C
With
methanol; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; trifluoroacetic acid; sodium hydroxide;
pyridine;
In
tetrachloromethane; ethanol; dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: trifluoroacetic acid / 24 h / 80 °C
2: pyridine / dichloromethane / 8 h / 0 - 20 °C
3: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / tetrachloromethane / 2.5 h / Reflux; Irradiation
4: potassium carbonate; methanol / 2 h / 20 °C
With
methanol; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); potassium carbonate; trifluoroacetic acid;
pyridine;
In
tetrachloromethane; dichloromethane;
