2-[(diethylcarbamoyl)oxy]-N,N,N-trimethylethanaminium iodide

Base Information

• Chemical Name: 2-[(diethylcarbamoyl)oxy]-N,N,N-trimethylethanaminium iodide
• CAS No.: 63981-51-1
• Molecular Formula: C₁₀H₂₃N₂O₂*I
• Molecular Weight: 330.209
• Mol file: 63981-51-1.mol

Synonyms:Choline,iodide diethylcarbamate (6CI); Ethanaminium, 2-[[(diethylamino)carbonyl]oxy]-N,N,N-trimethyl-,iodide (9CI)

Chemical Property of 2-[(diethylcarbamoyl)oxy]-N,N,N-trimethylethanaminium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-[(diethylcarbamoyl)oxy]-N,N,N-trimethylethanaminium iodide

There total 4 articles about 2-[(diethylcarbamoyl)oxy]-N,N,N-trimethylethanaminium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

Diethyl-carbamic acid 2-dimethylamino-ethyl ester (76866-73-4) + methyl iodide (74-88-4) → N,N-diethylcarbacholine (63981-51-1)

Guidance literature:

In ethanol; at 40 ℃;

DOI:10.1002/ardp.19963290207

Reference yield:

diethyl-carbamic acid-(2-chloro-ethyl ester) (20485-87-4) → N,N-diethylcarbacholine (63981-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; NaI

2: acetone

With methanol; acetone; sodium iodide;

DOI:10.1021/ja01853a064

Reference yield:

diethyl-carbamic acid-(2-iodo-ethyl ester) (89940-54-5) + trimethylamine (75-50-3) → N,N-diethylcarbacholine (63981-51-1)

Guidance literature:

With acetone;

DOI:10.1021/ja01853a064

upstream raw materials:

diethyl-carbamic acid-(2-iodo-ethyl ester)

trimethylamine

Diethyl-carbamic acid 2-dimethylamino-ethyl ester

methyl iodide