trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

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Chemical Name:trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine
CAS No.:1418199-79-7
Molecular Formula:C₂₂H₂₁N₅O₅S
Molecular Weight:467.505
Hs Code.:

Synonyms:trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

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Chemical Property of trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

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Technology Process of trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

There total 3 articles about trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1245649-52-8
1-(benzenesulfonyl)-4-chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine

: 1418200-48-2
trans-4-oxazol-5-yl-cyclohexylamine

: 1418199-79-7
trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In isopropyl alcohol; at 80 ℃; for 3h;

Reference yield:

: 181308-57-6
trans-(4-formyl-cyclohexyl)-carbamic acid tert-butyl ester

: 1418199-79-7
trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / 2 h / 65 °C

2: trifluoroacetic acid / dichloromethane / 0.67 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 3 h / 80 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; isopropyl alcohol;

Reference yield:

: 1418200-47-1
trans-(4-oxazol-5-yl-cyclohexyl)-carbamic acid tert-butyl ester

: 1418199-79-7
trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 0.67 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 3 h / 80 °C

With N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; isopropyl alcohol;