trans-1-benzenesulfonyl-N4-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

Base Information

Chemical Name:trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine
CAS No.:1418199-80-0
Molecular Formula:C₂₂H₂₃N₅O₃S
Molecular Weight:437.522
Hs Code.:

Synonyms:trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

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Chemical Property of trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

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Technology Process of trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

There total 4 articles about trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1418199-79-7
trans-(1-benzenesulfonyl-5-nitro-1H-pyrrolo[2,3-b]pyridin-4-yl)-(4-oxazol-5-yl-cyclohexyl)-amine

: 1418199-80-0
trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

Guidance literature:: With iron; ammonium chloride; In ethanol; for 1.5h; Reflux;

Reference yield:

: 181308-57-6
trans-(4-formyl-cyclohexyl)-carbamic acid tert-butyl ester

: 1418199-80-0
trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / 2 h / 65 °C

2: trifluoroacetic acid / dichloromethane / 0.67 h / 20 °C

3: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 3 h / 80 °C

4: ammonium chloride; iron / ethanol / 1.5 h / Reflux

With iron; potassium carbonate; ammonium chloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In ethanol; dichloromethane; isopropyl alcohol;

Reference yield:

: 1418200-47-1
trans-(4-oxazol-5-yl-cyclohexyl)-carbamic acid tert-butyl ester

: 1418199-80-0
trans-1-benzenesulfonyl-N*4*-(4-oxazol-5-yl-cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4,5-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / dichloromethane / 0.67 h / 20 °C

2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 3 h / 80 °C

3: ammonium chloride; iron / ethanol / 1.5 h / Reflux

With iron; ammonium chloride; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In ethanol; dichloromethane; isopropyl alcohol;