methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

Base Information

Chemical Name:methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate
CAS No.:1202033-66-6
Molecular Formula:C₂₆H₂₉FN₄O₅
Molecular Weight:496.538
Hs Code.:

Synonyms:methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

Suppliers and Price of methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

There total 1 articles about methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 1036757-02-4
tert-butyl 4-(6-bromo-2-(3-fluorophenylamino)quinazolin-7-yloxy)piperidine-1-carboxylate

: 1202033-66-6
methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

Guidance literature:: With triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; at 90 ℃; for 20h; under 25858.1 Torr;

Reference yield:

: 1202033-66-6
methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate

: 1202033-68-8
7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylic acid

Guidance literature:: methyl 7-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)-2-(3-fluorophenylamino)quinazoline-6-carboxylate; With lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 5h;

With hydrogenchloride; water; In acetonitrile; pH=5 - 6;