Cyclindole

Base Information

Chemical Name:Cyclindole
CAS No.:32211-97-5
Molecular Formula:C14H18 N2
Molecular Weight:214.31
Hs Code.:2933990090
UNII:CXJ7G6BYD7
DSSTox Substance ID:DTXSID10865627
Nikkaji Number:J19.791B
Wikipedia:Ciclindole
Wikidata:Q5119444
NCI Thesaurus Code:C81488
ChEMBL ID:CHEMBL2104160
Mol file:32211-97-5.mol

Synonyms:2,3,4,9-tetrahydro-N,N-dimethyl-1H-carbazole-3-amine;3-(dimethylamino)-1,2,3,4-tetrahydrocarbazole;cyclindole;cyclindole hydrochloride;Win 27,147-2

Suppliers and Price of Cyclindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CYCLINDOLE 95.00%
5MG
$ 503.29

Total 4 raw suppliers

Chemical Property of Cyclindole

Chemical Property:

Vapor Pressure:1.73E-05mmHg at 25°C
Melting Point:138-142 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling Point:364°Cat760mmHg
PKA:17.54±0.40(Predicted)
Flash Point:174°C
PSA：19.03000
Density:1.12g/cm³
LogP:2.58680
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:214.146998583
Heavy Atom Count:16
Complexity:251

Purity/Quality:

99% ^*data from raw suppliers

CYCLINDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1CCC2=C(C1)C3=CC=CC=C3N2
Uses Antidepressant.

Technology Process of Cyclindole

There total 4 articles about Cyclindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 100-63-0
phenylhydrazine

: 176661-76-0
(1,4-dioxa-spiro[4.5]dec-8-yl)dimethylamine

: 32211-97-5
N,N-dimethyl-(2,3,4,9-tetrahydro-1H-carbazole-3-yl)amine

Guidance literature:: With sulfuric acid; In water; at 95 - 100 ℃;
DOI:10.1016/j.bmcl.2012.06.002

Reference yield:

: 40594-34-1
4-(dimethylamino)cyclohexanone

: 32211-97-5
N,N-dimethyl-(2,3,4,9-tetrahydro-1H-carbazole-3-yl)amine

Guidance literature:: With phenylhydrazine; In acetic acid;

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 32211-97-5
N,N-dimethyl-(2,3,4,9-tetrahydro-1H-carbazole-3-yl)amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: deuteromethanol / 2 h / 20 °C

1.2: 18 h / 25 - 30 °C / pH Ca_. 6

2.1: sulfuric acid / water / 95 - 100 °C

With sulfuric acid; In deuteromethanol; water;
DOI:10.1016/j.bmcl.2012.06.002