S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate

Base Information

• Chemical Name: S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate
• CAS No.: 658071-60-4
• Molecular Formula: C₁₆H₁₇ClN₂O₂S₂
• Molecular Weight: 368.908

Synonyms:S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate

Chemical Property of S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate

There total 3 articles about S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

tiolacetic acid (507-09-5) + 1-benzyl-6-bromomethyl-5-chloro-3-(ethylsulfanyl)-2(1H)-pyrazinone (658071-59-1) → S1-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate (658071-60-4)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2003.11.005

Reference yield:

1-benzyl-3,5-dichloro-6-methylpyrazin-2(1H)-one (173200-35-6) → S1-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate (658071-60-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / tetrahydrofuran / 20 °C

2: 90 percent / N-bromosuccinimide; (PhCOO)2 / CCl₄ / Heating

3: 94 percent / triethylamine / tetrahydrofuran / 1 h / 20 °C

With N-Bromosuccinimide; triethylamine; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane;

DOI:10.1016/j.tet.2003.11.005

Reference yield:

1-benzyl-5-chloro-3-(ethylsulfanyl)-6-methyl-2(1H)-pyrazinone (658071-58-0) → S1-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate (658071-60-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / N-bromosuccinimide; (PhCOO)2 / CCl₄ / Heating

2: 94 percent / triethylamine / tetrahydrofuran / 1 h / 20 °C

With N-Bromosuccinimide; triethylamine; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane;

DOI:10.1016/j.tet.2003.11.005

upstream raw materials:

tiolacetic acid

1-benzyl-6-bromomethyl-5-chloro-3-(ethylsulfanyl)-2(1H)-pyrazinone

1-benzyl-3,5-dichloro-6-methylpyrazin-2(1H)-one

1-benzyl-5-chloro-3-(ethylsulfanyl)-6-methyl-2(1H)-pyrazinone

Downstream raw materials:

1-benzyl-5-chloro-3-(ethylsulfanyl)-6-[(2-propynylsulfanyl)methyl]-2(1H)-pyrazinone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 658071-60-4 S¹-{[1-benzyl-3-chloro-1,6-dihydro-5-(ethylsulfanyl)-6-oxo-2-pyrazinyl]methyl}ethanethioate

Send

Send

Metric Ton KG G Pound L ML

Send

Send