1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide

Base Information

• Chemical Name: 1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide
• CAS No.: 1215104-13-4
• Molecular Formula: C₁₅H₂₀N₂O₅
• Molecular Weight: 308.334
• Mol file: 1215104-13-4.mol

Synonyms:1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide

Chemical Property of 1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide

There total 1 articles about 1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethoxyethylamine (22483-09-6) + 1-(4-nitrophenyl)cyclobutanecarboxylic acid (202737-42-6) → 1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide (1215104-13-4)

Guidance literature:

1-(4-nitrophenyl)cyclobutanecarboxylic acid; With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

2,2-dimethoxyethylamine; With HATU; In dichloromethane; N,N-dimethyl-formamide; for 3h; Inert atmosphere;

Reference yield:

1-(4-nitro-phenyl)-cyclobutanecarboxylic acid (2,2-dimethoxy-ethyl)-amide (1215104-13-4) → 2-[1-(4-nitro-phenyl)-cyclobutyl]-oxazole (1215104-14-5)

Guidance literature:

With phosphorus pentoxide; at 135 ℃; for 5.5h; Inert atmosphere;

upstream raw materials:

2,2-dimethoxyethylamine

1-(4-nitrophenyl)cyclobutanecarboxylic acid

Downstream raw materials:

2-[1-(4-nitro-phenyl)-cyclobutyl]-oxazole