4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Base Information

Chemical Name:4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate
CAS No.:1447733-07-4
Molecular Formula:C₂HF₃O₂*C₁₈H₁₈N₂O₄
Molecular Weight:440.376
Hs Code.:

Synonyms:4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Suppliers and Price of 4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

There total 4 articles about 4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₃₄N₂O₆

: 76-05-1
trifluoroacetic acid

: 1447733-07-4
4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Guidance literature:: In dichloromethane; for 2h;

Reference yield:

: 350014-19-6
methyl N-(tert-butyloxycarbonyl)-6-hydroxy-3,4-dihydro-1H-isoquinoline-1-carboxylate

: 1447733-07-4
4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 - 20 °C

1.2: 16 h / 20 °C

2.1: methanol; lithium hydroxide monohydrate / tetrahydrofuran / 12 h

3.1: pyridine; trichlorophosphate / 2 h / -10 °C

4.1: dichloromethane / 2 h

With pyridine; methanol; lithium hydroxide monohydrate; sodium hydride; trichlorophosphate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 531556-16-8
C₁₇H₂₃NO₅

: 1447733-07-4
4-(6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid trifluoracetate

Guidance literature:: Multi-step reaction with 3 steps

1: methanol; lithium hydroxide monohydrate / tetrahydrofuran / 12 h

2: pyridine; trichlorophosphate / 2 h / -10 °C

3: dichloromethane / 2 h

With pyridine; methanol; lithium hydroxide monohydrate; trichlorophosphate; In tetrahydrofuran; dichloromethane;