2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

Base Information

Chemical Name:2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester
CAS No.:863203-65-0
Molecular Formula:C₂₀H₁₇NO₅
Molecular Weight:351.359
Hs Code.:

Synonyms:2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

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Chemical Property of 2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

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Technology Process of 2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

There total 1 articles about 2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 23981-80-8
naproxen

: 863203-65-0
2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1002/anie.201910821

Reference yield: 93.0%

: 91-01-0
1,1-Diphenylmethanol

: 863203-65-0
2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

: (R)-benzhydryl 2-(6-methoxynaphthalen-2-yl)propanoate

Guidance literature:: With (R)-5-benzyl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; caesium carbonate; In chloroform; at 24 - 26 ℃; for 24h; Reagent/catalyst; enantioselective reaction; Mechanism; Molecular sieve; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1021/jacs.6b00406

Reference yield:

: 863203-65-0
2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester

: C₂₀H₁₇NO₅

: 951305-30-9
C₂₀H₁₇NO₅

: 22204-53-1
(2S)-2-(6-methoxy(2-naphthyl))propanoic acid

: 23979-41-1
(R)-2-(6-methoxy-2-naphthyl)propionic acid

Guidance literature:: 2-(6-Methoxy-naphthalen-2-yl)-propionic acid 4-nitro-phenyl ester; With Pseudomonas aeruginosa lipase Met₁₆Ala/Leu₁₇Phe/Leu₁₆₂Asn mutant; In acetonitrile; at 30 ℃; for 1.5h; pH=7.5; aq. phosphate buffer; Resolution of racemate; Enzymatic reaction;

With hydrogenchloride; In water; acetonitrile; enantioselective reaction;
DOI:10.1021/ja1030479