methyl 2,4-diisopropoxyphenylacetate

Base Information

• Chemical Name: methyl 2,4-diisopropoxyphenylacetate
• CAS No.: 728911-60-2
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 728911-60-2.mol

Synonyms:methyl 2,4-diisopropoxyphenylacetate

Chemical Property of methyl 2,4-diisopropoxyphenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,4-diisopropoxyphenylacetate

There total 2 articles about methyl 2,4-diisopropoxyphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methanol (67-56-1) + 2,4-diisopropoxyacetophenone (728911-59-9) → methyl 2,4-diisopropoxyphenylacetate (728911-60-2)

Guidance literature:

With perchloric acid; thallium(III) nitrate; In methanol; at 20 ℃; for 4.3h;

DOI:10.3987/com-04-10060

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → methyl 2,4-diisopropoxyphenylacetate (728911-60-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / K₂CO₃ / dimethylformamide / 3.3 h / 55 °C

2: 82 percent / thallium trinitrate; aq. perchloric acid / methanol / 4.3 h / 20 °C

With perchloric acid; potassium carbonate; thallium(III) nitrate; In methanol; N,N-dimethyl-formamide;

DOI:10.3987/com-04-10060

Reference yield: 99.0%

methyl 2,4-diisopropoxyphenylacetate (728911-60-2) → methyl 5-bromo-2,4-diisopropoxyphenylacetate (728911-82-8)

Guidance literature:

With N-Bromosuccinimide; SiO₂ (Micro Bead 3 Angstroem); In chloroform; at 20 ℃; for 1.16667h;

DOI:10.3987/com-04-10060

upstream raw materials:

methanol

2,4-diisopropoxyacetophenone

2',4'-dihydroxy-4-acetophenone

Downstream raw materials:

2,4-diisoproxyphenylacetic acid

methyl 5-bromo-2,4-diisopropoxyphenylacetate

2,4-diisopropoxyphenylacetyl chloride

5-bromo-2,4-diisopropoxyphenylacetic acid