meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Base Information

Chemical Name:meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester
CAS No.:244153-94-4
Molecular Formula:C₁₈H₂₇NO₇
Molecular Weight:369.415
Hs Code.:

Synonyms:meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Suppliers and Price of meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

There total 6 articles about meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 244153-85-3
meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal

: 244153-94-4
meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 81 percent / DMAP / CH₂Cl₂ / 2 h

2: hydrogen / Raney nickel / tetrahydrofuran / 14 h / 60 °C / 760 Torr

3: 3.24 g / pyridine / 1 h / Heating

4: aqueous acetic acid / 1 h / 20 °C / ultrasound

5: 144 mg / triethylamine / CH₂Cl₂ / 14 h / 20 °C

With pyridine; dmap; hydrogen; acetic acid; triethylamine; nickel; In tetrahydrofuran; dichloromethane; 1: Acetylation / 2: Reduction / 3: Acetylation / 4: deacetalization / 5: Wittig olefination;
DOI:10.1021/jo990293i

Reference yield:

: 244153-90-0
meso-(1r,2R,6S)-2,6-diacetoxy-1-nitrocyclohexane-1-acetaldehyde 1,3-propanediol acetal

: 244153-94-4
meso-(E)-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-2-butenoic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen / Raney nickel / tetrahydrofuran / 14 h / 60 °C / 760 Torr

2: 3.24 g / pyridine / 1 h / Heating

3: aqueous acetic acid / 1 h / 20 °C / ultrasound

4: 144 mg / triethylamine / CH₂Cl₂ / 14 h / 20 °C

With pyridine; hydrogen; acetic acid; triethylamine; nickel; In tetrahydrofuran; dichloromethane; 1: Reduction / 2: Acetylation / 3: deacetalization / 4: Wittig olefination;
DOI:10.1021/jo990293i