meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal

Base Information

• Chemical Name: meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal
• CAS No.: 244153-85-3
• Molecular Formula: C₁₁H₁₉NO₆
• Molecular Weight: 261.275
• Mol file: 244153-85-3.mol

Synonyms:meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal

Chemical Property of meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal

There total 1 articles about meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-(2-nitroethyl)-1,3-dioxane (146073-16-7) + Glutaraldehyde (111-30-8,29257-65-6,79215-57-9) → meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal (244153-85-3)

Guidance literature:

With N,N,N',N'-tetramethylguanidine; In tetrahydrofuran;

DOI:10.1021/jo990293i

Reference yield: 99.0%

benzoyl chloride (98-88-4) + meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal (244153-85-3) → meso-(1r,2R,6S)-2,6-dibenzoyloxy-1-nitrocyclohexane-1-acetaldehyde 1,3-propanediol acetal

Guidance literature:

With dmap; In dichloromethane; for 2h;

DOI:10.1021/jo990293i

Reference yield: 81.0%

acetyl chloride (75-36-5) + meso-(1r,2R,6S)-1-nitrocyclohexane-2,6-diol-1-acetaldehyde 1,3-propanediol acetal (244153-85-3) → meso-(1r,2R,6S)-2,6-diacetoxy-1-nitrocyclohexane-1-acetaldehyde 1,3-propanediol acetal (244153-90-0)

Guidance literature:

With dmap; In dichloromethane; for 2h;

DOI:10.1021/jo990293i

upstream raw materials:

2-(2-nitroethyl)-1,3-dioxane

Glutaraldehyde

Downstream raw materials:

meso-(1r,2R,6S)-2,6-diacetoxy-1-nitrocyclohexane-1-acetaldehyde 1,3-propanediol acetal

4-((1R,2R,6S)-1-Amino-2,6-dihydroxy-cyclohexyl)-butyric acid

meso-(1r,2R,6S)-1-acetamido-2,6-diacetoxycyclohexane-1-acetaldehyde 1,3-propanediol acetal

(-)-(6S,12S)-12-phenoxythionocarbonyloxy-7-aza-1,4-dioxadispiro[4,0,5,4]pentadecan-8-one