trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine

Base Information

• Chemical Name: trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine
• CAS No.: 106589-70-2
• Molecular Formula: C₃₅H₂₅NO₄
• Molecular Weight: 523.588
• Mol file: 106589-70-2.mol

Synonyms:trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine

Chemical Property of trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine

There total 7 articles about trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-dimethylaminomethyl-naphthalen-2-ol (5419-02-3) → trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine (106589-70-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 0.5 g / 0.5 h / 260 - 280 °C

2: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

3: 1.) Na, NH₃ liq., 2.) AcOH / 1.) THF, 18 h, 2.) 100 deg C to 125 deg C, 18 h

4: 1.) t-BuONa, 2.) DDQ / 1.) t-BuOH, reflux, 15 h, 2.) dioxane, reflux, 15 h

5: 83 mg / I₂ / benzene / 12 h / Heating

With ammonia; iodine; sodium; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium t-butanolate; palladium on activated charcoal; In benzene;

DOI:10.1021/jo00382a017

Reference yield:

1,2,3,4-tetrahydrodibenzacridine (105467-77-4) → trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine (106589-70-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

2: 1.) Na, NH₃ liq., 2.) AcOH / 1.) THF, 18 h, 2.) 100 deg C to 125 deg C, 18 h

3: 1.) t-BuONa, 2.) DDQ / 1.) t-BuOH, reflux, 15 h, 2.) dioxane, reflux, 15 h

4: 83 mg / I₂ / benzene / 12 h / Heating

With ammonia; iodine; sodium; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium t-butanolate; palladium on activated charcoal; In benzene;

DOI:10.1021/jo00382a017

Reference yield:

6-amino-1,2,3,4-tetrahydronaphthalene (2217-43-8) → trans-1,2-bis(benzoyloxy)-1,2,3,4-tetrahydrodibenzacridine (106589-70-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 0.5 g / 0.5 h / 260 - 280 °C

2: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

3: 1.) Na, NH₃ liq., 2.) AcOH / 1.) THF, 18 h, 2.) 100 deg C to 125 deg C, 18 h

4: 1.) t-BuONa, 2.) DDQ / 1.) t-BuOH, reflux, 15 h, 2.) dioxane, reflux, 15 h

5: 83 mg / I₂ / benzene / 12 h / Heating

With ammonia; iodine; sodium; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium t-butanolate; palladium on activated charcoal; In benzene;

DOI:10.1021/jo00382a017

upstream raw materials:

silver benzoate

3,4-dihydrodibenzacridine

1-dimethylaminomethyl-naphthalen-2-ol

dibenz[a,j]acridine

Downstream raw materials:

trans-1,2-dihydro-1,2-dihydroxydibenzacridine