N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine

Base Information

• Chemical Name: N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine
• CAS No.: 1219503-99-7
• Molecular Formula: C₂₂H₂₇ClN₄
• Molecular Weight: 382.936

Synonyms:N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine

Chemical Property of N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine

Chemical Property:

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Technology Process of N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine

There total 1 articles about N₁-[2-(7-chloroquinolin-4-ylamino)ethyl]-N₃,N₃-dimethyl-1-phenylpropane-1,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-(7-chloroquinolin-4-yl)ethylenediamine (5407-57-8) + 3-(dimethylamino)-1-phenylpropyl chloride hydrochloride (1011-59-2) → N1-[2-(7-chloroquinolin-4-ylamino)ethyl]-N3,N3-dimethyl-1-phenylpropane-1,3-diamine (1219503-99-7)

Guidance literature:

With triethylamine; In ethanol; at 20 ℃; for 40h;

DOI:10.1021/jm9018383

Reference yield:

N1-[2-(7-chloroquinolin-4-ylamino)ethyl]-N3,N3-dimethyl-1-phenylpropane-1,3-diamine (1219503-99-7) → N1-[2-(7-chloro-quinolin-4-ylamino)-ethyl]-N3,N3-dimethyl-1-phenyl-propane-1,3-diamine trihydrochloride

Guidance literature:

With methanol; chloro-trimethyl-silane;

DOI:10.1021/jm9018383

upstream raw materials:

N-(7-chloroquinolin-4-yl)ethylenediamine

3-(dimethylamino)-1-phenylpropyl chloride hydrochloride

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