Chemical Property of 7-Ethoxycoumarin
Chemical Property:
- Appearance/Colour:Beige crystalline powder
- Vapor Pressure:6.36E-05mmHg at 25°C
- Melting Point:88-90 °C(lit.)
- Refractive Index:1.561
- Boiling Point:344.962 °C at 760 mmHg
- Flash Point:143.132 °C
- PSA：39.44000
- Density:1.207 g/cm3
- LogP:2.19170
- Storage Temp.:Sealed in dry,Room Temperature
- Solubility.:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
- Water Solubility.:Soluble in hot methanol (very faint turbidity), 95% ethanol (50 mg/ml), DMF, and DMSO. Insoluble in water.
- XLogP3:2.3
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:2
- Exact Mass:190.062994177
- Heavy Atom Count:14
- Complexity:247
- Purity/Quality:
-
97% *data from raw suppliers
7-Ethoxycoumarin 99+% *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Dyes -> Coumarin Dyes
- Canonical SMILES:CCOC1=CC2=C(C=C1)C=CC(=O)O2
-
Uses
7-Ethoxycoumarin is a substrate for CYP2B6 used in fluorometric assays of microsomal monooxygenase activity. 7-Ethoxycoumarin is commonly used for metabolism studies, including hepatocyte studies, liver perfusion techniques and cytochrome P450 studies.7-Ethoxycoumarin has been used to study the functional activity of recombinant P450. ) It has also been used as an internal standard for in vitro S-warfarin 7-hydroxylation and high performance liquid chromatography (HPLC) analysis.
