trans-3-chloroallyl 2,3-epoxypropyl ether

Base Information

• Chemical Name: trans-3-chloroallyl 2,3-epoxypropyl ether
• CAS No.: 108788-73-4
• Molecular Formula: C₆H₉ClO₂
• Molecular Weight: 148.589
• Mol file: 108788-73-4.mol

Synonyms:trans-3-chloroallyl 2,3-epoxypropyl ether

Chemical Property of trans-3-chloroallyl 2,3-epoxypropyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of trans-3-chloroallyl 2,3-epoxypropyl ether

There total 4 articles about trans-3-chloroallyl 2,3-epoxypropyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-fluoroethanol (371-62-0) + 2-fluoro-2-phenylethanol (2932-58-3) → trans-3-chloroallyl 2,3-epoxypropyl ether (108788-73-4) + 2-(2-Fluoro-2-phenyl-ethoxymethyl)-oxirane (128367-32-8) + oxiranyl-methanol (556-52-5)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; at 25 ℃; for 24h; Yields of byproduct given;

DOI:10.1016/S0022-1139(00)80459-5

Reference yield: 65.0%

2-fluoroethanol (371-62-0) + trans-2-fluorocyclohexanol (14365-32-3) → 2-((1S,2S)-2-Fluoro-cyclohexyloxymethyl)-oxirane (128920-99-0) + trans-3-chloroallyl 2,3-epoxypropyl ether (108788-73-4) + oxiranyl-methanol (556-52-5)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; at 25 ℃; for 24h; Yields of byproduct given;

DOI:10.1016/S0022-1139(00)80459-5

Reference yield: 24.0%

2-(phenylsulfanylmethyl)oxirane (5296-21-9) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → trans-3-chloroallyl 2,3-epoxypropyl ether (108788-73-4) + trans-1-phenylthio-6,7-epoxy-4-oxahept-1-ene

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In 1,4-dioxane; at 70 ℃; for 2h;

DOI:10.1246/bcsj.60.667

upstream raw materials:

2-fluoroethanol

2-fluoro-2-phenylethanol

trans-2-fluorocyclohexanol

2-(phenylsulfanylmethyl)oxirane