(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

Base Information

Chemical Name:(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole
CAS No.:208465-04-7
Molecular Formula:C₃₁H₃₇N₃O₃
Molecular Weight:499.653
Hs Code.:

Synonyms:(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

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Chemical Property of (S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

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Technology Process of (S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

There total 3 articles about (S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 208465-07-0
4-tributylstannanyl-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester

: 208464-45-3
(S)-5-bromo-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

: 208465-04-7
(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 100 - 110 ℃;

Reference yield:

: 208464-41-9,312949-16-9
(S)-5-Bromo-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole

: 208465-04-7
(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

Guidance literature:: Multi-step reaction with 2 steps

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 100 - 110 °C

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene;

Reference yield:

: 199659-03-5,331842-86-5
3-(N-benzyloxycarbonylpyrrolidin-2S-ylcarbonyl)-5-bromo-1H-indole

: 208465-04-7
(S)-5-(1-aza-1-tert-butoxycarbonylcyclohex-3-en-4-yl)-3-[(N-methylpyrrolidin-2-yl)methyl]-1-benzoylindole

Guidance literature:: Multi-step reaction with 3 steps

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 100 - 110 °C

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene;