1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole

Base Information

• Chemical Name: 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole
• CAS No.: 97801-18-8
• Molecular Formula: C₂₅H₂₈Cl₂N₄O₇
• Molecular Weight: 567.426

Synonyms:1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole

Chemical Property of 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole

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Technology Process of 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole

There total 1 articles about 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

2-(2-azidoethoxy)methyl-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine (88150-49-6) + propynoic acid ethyl ester (623-47-2) → 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-5-(ethoxycarbonyl)-1,2,3-triazole (97801-19-9) + 1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole (97801-18-8)

Guidance literature:

In toluene; for 6h; Heating;

DOI:10.1021/jm00168a041

Reference yield: 68.0%

1-<2-<<4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-4-(ethoxycarbonyl)-1,2,3-triazole (97801-18-8) → 2-[2-(4-Carbamoyl-[1,2,3]triazol-1-yl)-ethoxymethyl]-4-(2,3-dichloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester (97801-22-4)

Guidance literature:

With ammonium hydroxide; In 1,4-dioxane; for 24h; Ambient temperature;

DOI:10.1021/jm00168a041

upstream raw materials:

2-(2-azidoethoxy)methyl-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

propynoic acid ethyl ester

Downstream raw materials:

2-[2-(4-Carbamoyl-[1,2,3]triazol-1-yl)-ethoxymethyl]-4-(2,3-dichloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester

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