(2S,3S)-2-ethyl-3-methyl valeric acid

Base Information

• Chemical Name: (2S,3S)-2-ethyl-3-methyl valeric acid
• CAS No.: 210537-43-2
• Molecular Formula: C₈H₁₆O₂
• Molecular Weight: 144.214
• Mol file: 210537-43-2.mol

Synonyms:(2S,3S)-2-ethyl-3-methyl valeric acid

Chemical Property of (2S,3S)-2-ethyl-3-methyl valeric acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (2S,3S)-2-ethyl-3-methyl valeric acid

There total 1 articles about (2S,3S)-2-ethyl-3-methyl valeric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

C25H31N2O3Pol → (R)-arundic acid + (2S,3S)-2-ethyl-3-methyl valeric acid (210537-43-2)

Guidance literature:

With dihydrogen peroxide; lithium hydroxide; In tetrahydrofuran; water; at 0 - 20 ℃; non-cross-linked polystyrene (NCPS)

DOI:10.3184/174751914X13975731462355

Reference yield:

pseudoephedrine (90-82-4,7009-81-6,90-83-5,6912-63-6) + pivaloyl chloride (3282-30-2) + (2S,3S)-2-ethyl-3-methyl valeric acid (210537-43-2) → (2R,3S)-2-ethyl-3-methylpentanoic acid ((1'S,2'S)-2'-hydroxy-1'-methyl-2'-phenylethyl)(methyl)amide (1122577-97-2) + (1S,2S)-1-Phenyl-2-(methylpivaloylamino)propanol

Guidance literature:

pivaloyl chloride; (2S,3S)-2-ethyl-3-methyl valeric acid; With triethylamine; In dichloromethane; at -5 - 0 ℃; Inert atmosphere;

pseudoephedrine; With triethylamine; In dichloromethane; at 5 ℃; Inert atmosphere;

DOI:10.1021/op800260j

Downstream raw materials:

(2R,3S)-2-ethyl-3-methylpentanoic acid ((1'S,2'S)-2'-hydroxy-1'-methyl-2'-phenylethyl)(methyl)amide