(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

Base Information

Chemical Name:(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt
CAS No.:1351764-67-4
Molecular Formula:C₃₄H₃₆FN₂O₆*Na
Molecular Weight:610.658
Hs Code.:

(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

Synonyms:(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

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Chemical Property of (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

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Technology Process of (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

There total 2 articles about (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 936756-74-0
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-4-{[4-(hydroxymethyl)phenyl]carbamoyl}-3-phenyl-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate

: 1351764-67-4
(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

Guidance literature:: With methanol; sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield:

: 805241-63-8
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-4-{[4-(hydroxymethyl)phenyl]carbamoyl}-3-phenyl-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate

: 1351764-67-4
(3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethyl-phenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid sodium salt

Guidance literature:: tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-4-{[4-(hydroxymethyl)phenyl]carbamoyl}-3-phenyl-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate; With hydrogenchloride; In tetrahydrofuran; methanol; at 0 - 20 ℃;

With sodium hydroxide; In tetrahydrofuran; methanol; at 0 ℃;