(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Base Information

Chemical Name:(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate
CAS No.:1403479-90-2
Molecular Formula:C₁₇H₂₈FNO₅SSi
Molecular Weight:405.563
Hs Code.:

Synonyms:(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Suppliers and Price of (R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Chemical Property:

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Technology Process of (R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

There total 3 articles about (R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 349-88-2
4-Fluorobenzenesulfonyl chloride

: 1403482-02-9
(R)-methyl 4-amino-3-((tert-butyldimethylsilyl)oxy)butanoate

: 1403479-90-2
(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 916971-31-8
(R)-methyl 4-amino-3-hydroxybutanoate

: 1403479-90-2
(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 20 °C

2: triethylamine / dichloromethane / 16 h / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1021/jm500994n

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1403479-90-2
(R)-methyl 3-((tertbutyldimethylsilyl)oxy)-4-(4-fluorophenylsulfonamido)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 2 h / 20 °C

2: triethylamine / dichloromethane / 16 h / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1021/jm500994n