3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

Base Information

Chemical Name:3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile
CAS No.:1403679-87-7
Molecular Formula:C₁₆H₁₈ClF₃N₂O₂
Molecular Weight:362.779
Hs Code.:

Synonyms:3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

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Chemical Property of 3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

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Technology Process of 3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

There total 2 articles about 3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1403679-86-6
3-(2-chloro-5-(trifluoromethyl)phenyl)-3-oxopropanenitrile

: 645-36-3
2,2-diethoxy-ethanamine

: 1403679-87-7
3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

Guidance literature:: In toluene; for 5h; Inert atmosphere; Reflux;

Reference yield:

: 26107-79-9
methyl 2-chloro-5-trifluoromethyl-benzoate

: 1403679-87-7
3-[2-chloro-5-(trifluoromethyl)phenyl]-3-[(2,2-diethoxyethyl)amino]prop-2-enenitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium 2-methylbutan-2-olate / toluene / 0.33 h / 20 °C

2: toluene / 5 h / Inert atmosphere; Reflux

With potassium 2-methylbutan-2-olate; In toluene;