Kumujancine

Base Information

Chemical Name:Kumujancine
CAS No.:92631-69-1
Molecular Formula:C₁₃H₁₀N₂O₂
Molecular Weight:226.235
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80239078
Nikkaji Number:J389.856C
Wikidata:Q83121418
Mol file:92631-69-1.mol

Synonyms:kumujancine;kumujansine

Suppliers and Price of Kumujancine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
4-methoxy-9H-Pyrido[3,4-b]indole-1-carboxaldehyde 97.00%
25G
$ 5520.00

AccelPharmtech
4-methoxy-9H-Pyrido[3,4-b]indole-1-carboxaldehyde 97.00%
1G
$ 1740.00

Total 3 raw suppliers

Chemical Property of Kumujancine

Chemical Property:

Vapor Pressure:1.23E-09mmHg at 25°C
Boiling Point:487°Cat760mmHg
Flash Point:248.3°C
PSA：54.98000
Density:1.372g/cm³
LogP:2.53720
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:226.074227566
Heavy Atom Count:17
Complexity:297

Purity/Quality:: 4-methoxy-9H-Pyrido[3,4-b]indole-1-carboxaldehyde 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CN=C(C2=C1C3=CC=CC=C3N2)C=O

Technology Process of Kumujancine

There total 6 articles about Kumujancine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 694533-86-3
ethyl 4-methoxy-β-carboline-1-carboxylate

: 92631-69-1
4-methoxy-β-carboline-1-carbaldehyde

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at -78 ℃;
DOI:10.1016/j.bmcl.2004.01.055

Reference yield: 70.0%

: 60807-25-2
4-methoxy-β-carboline-1-carboxylic acid methyl ester

: 92631-69-1
4-methoxy-β-carboline-1-carbaldehyde

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at -40 ℃; for 0.0833333h;
DOI:10.1055/s-2004-834915

Reference yield:

: 343-94-2
tryptamine hydochloride

: 92631-69-1
4-methoxy-β-carboline-1-carbaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1.1: ethanol; toluene / 20 °C

2.1: 11.0 g / DMAP; Et₃N / CH₂Cl₂ / 20 °C

3.1: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone; water / tetrahydrofuran / -78 - 20 °C

4.1: p-toluenesulfonic acid / benzene / 0.5 h / 20 °C

4.2: 884 mg / p-chloranil / benzene / 20 °C

5.1: 96 percent / DIBAL-H / CH₂Cl₂; hexane / 0.17 h / -50 °C

With dmap; water; diisobutylaluminium hydride; toluene-4-sulfonic acid; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; ethanol; hexane; dichloromethane; toluene; benzene; 1.1: Pictet-Spengler reaction;
DOI:10.1248/cpb.53.653