henicosan-4-one

Base Information

• Chemical Name: henicosan-4-one
• CAS No.: 32822-45-0
• Molecular Formula: C₂₁H₄₂O
• Molecular Weight: 310.564
• Mol file: 32822-45-0.mol

Synonyms:henicosan-4-one

Chemical Property of henicosan-4-one

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of henicosan-4-one

There total 6 articles about henicosan-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-(1-oxooctadecyl)morpholine (5299-54-7) + 1-propylmagnesium chloride (2234-82-4) → henicosan-4-one (32822-45-0)

Guidance literature:

1-propylmagnesium chloride; With cerium(III) chloride; In tetrahydrofuran; at -78 ℃; for 2h;

4-(1-oxooctadecyl)morpholine; In tetrahydrofuran; at -78 ℃; for 1.5h; Further stages.;

DOI:10.1021/jo0263061

Reference yield:

stearic acid (57-11-4) → henicosan-4-one (32822-45-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: thionyl chloride / benzene / 24 h / 50 °C

2.1: pyridine / CHCl₃ / 20 h / 20 °C

3.1: CeCl₃*7H₂O / tetrahydrofuran / 2 h / -78 °C

3.2: 90 percent / tetrahydrofuran / 1.5 h / -78 °C

With pyridine; thionyl chloride; cerium(III) chloride; In tetrahydrofuran; chloroform; benzene;

DOI:10.1021/jo0263061

Reference yield:

Stearoyl chloride (112-76-5) → henicosan-4-one (32822-45-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine / CHCl₃ / 20 h / 20 °C

2.1: CeCl₃*7H₂O / tetrahydrofuran / 2 h / -78 °C

2.2: 90 percent / tetrahydrofuran / 1.5 h / -78 °C

With pyridine; cerium(III) chloride; In tetrahydrofuran; chloroform;

DOI:10.1021/jo0263061

upstream raw materials:

stearic acid

butyric acid

heneicosan-4-ol

4-(1-oxooctadecyl)morpholine

Downstream raw materials:

heneicosane