dl-Codamine

Base Information

Chemical Name:dl-Codamine
CAS No.:21040-59-5
Molecular Formula:C20H25NO4
Molecular Weight:343.423
Hs Code.:
NSC Number:127489
UNII:5D6TH19ZX4
DSSTox Substance ID:DTXSID90871988
Nikkaji Number:J1.990.552G
Wikidata:Q27261862
Metabolomics Workbench ID:46621
Mol file:21040-59-5.mol

Synonyms:5977-85-5;dl-Codamine;1-(3,4-Dimethoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol;(+/-)-Codamine;Codamine, DL-;Codamine, (RS)-;Codamine DL-form [MI];Codamine, (+/-)-;NSC-127489;UNII-5D6TH19ZX4;(S)-Codamine;5D6TH19ZX4;(.+-.)-Codamine;1-((3,4-Dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinol;1-[(3,4-dimethoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol;7-Isoquinolinol, 1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6-methoxy-2-methyl-;1-[(3,4-dimethoxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol;1-[(3,4-dimethoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoq uinolin-7-ol;Kodamin;NSC127489;Codamine, (.+-.)-;SCHEMBL680513;DTXSID90871988;AKOS000277676;Q27261862;7-Isoquinolinol,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6-methoxy-2-methyl-, (.+-.)-

Suppliers and Price of dl-Codamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of dl-Codamine

Chemical Property:

Melting Point:127°C
Refractive Index:1.5614 (estimate)
Boiling Point:478.69°C (rough estimate)
PKA:10.21±0.40(Predicted)
Density:1.1867 (rough estimate)
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:343.17835828
Heavy Atom Count:25
Complexity:421

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)O)OC

Technology Process of dl-Codamine

There total 2 articles about dl-Codamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5977-85-5
(+/-)-Codamine

: (R)-1-(3,4-Dimethoxy-benzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol

: 21040-59-5
(+)-codamine

Guidance literature:: With water; In 2,2,4-trimethylpentane; benzene; at 33 ℃; for 3h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Amano AY-30 lipase from Candida cylindracea immobilized with celite;
DOI:10.1016/S0957-4166(00)80135-4

Reference yield:

: 21040-59-5
(+)-codamine

Guidance literature:: Darst_. aus der aether.Mutterlauge des Laudanins; man befreit es von beigemengtem Mekonidin durch Kochen mit verd.Schwefelsaeure;