(E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene

Base Information

• Chemical Name: (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene
• CAS No.: 121402-00-4
• Molecular Formula: C₁₆H₂₆
• Molecular Weight: 218.382
• Mol file: 121402-00-4.mol

Synonyms:(E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene

Chemical Property of (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene

There total 12 articles about (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(3'E,5'E,7'E)-2-(3',7'-dimethyldeca-3',5',7',9'-tetraen-1'-yl)-1,3,3-trimethylcyclohex-1-ene (1376709-64-6) → 1,3,3-trimethyl-2-(3'-methylbut-3'-en-1'-yl)cyclohex-1-ene + 7,8,7',8'-tetrahydro-β,β-carotene (127000-61-7,40772-88-1) + (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene (121402-00-4)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 50 ℃; for 5h;

DOI:10.1021/np300230t

Reference yield: 59.0%

(E)-3-methyl-5-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)pent-2-enal (28290-33-7,56522-85-1,28290-32-6) + Methyltriphenylphosphonium bromide (1779-49-3) → (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene (121402-00-4)

Guidance literature:

Methyltriphenylphosphonium bromide; With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; n-butyllithium; In tetrahydrofuran; hexane; at -78 - 25 ℃; for 0.5h;

(E)-3-methyl-5-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)pent-2-enal; In tetrahydrofuran; hexane; at -78 - 25 ℃; for 2h;

DOI:10.1021/np300230t

Reference yield:

4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on (17283-81-7) + allyldiphenylphosphine oxide (4141-48-4) → (E)-1,3,3-trimethyl-2-(3'-methylhexa-3',5'-dien-1-yl)cyclohex-1-ene (121402-00-4)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at -78 ℃; for 0.25h;

DOI:10.1016/S0040-4039(00)87892-2

upstream raw materials:

4-(2,6,6-Trimethyl-cyclohex-1-enyl)-butan-2-on

allyldiphenylphosphine oxide

(2E,4E,6E)-3,7-dimethyl-9-(2',6',6'-trimethylcyclohex-1'-en-1'-yl)nona-2,4,6-trien-1-ol

(3'E,5'E,7'E)-2-(3',7'-dimethyldeca-3',5',7',9'-tetraen-1'-yl)-1,3,3-trimethylcyclohex-1-ene

Downstream raw materials:

(E)-2-[(S)-3-(tert-Butyl-dimethyl-silanyloxy)-3-(5-oxo-2,5-dihydro-furan-3-yl)-prop-(E)-ylidene]-6-methyl-8-(trimethyl-cyclohex-1-enyl)-oct-5-enoic acid benzyl ester

(E)-2-[(S)-3-(tert-Butyl-dimethyl-silanyloxy)-3-(5-oxo-2,5-dihydro-furan-3-yl)-prop-(E)-ylidene]-6-methyl-8-(trimethyl-cyclohex-1-enyl)-oct-5-enoic acid benzyl ester

4S-manoalide diol

1-bromo-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)-3-hexene