C₃₄H₅₈O₈Si₂

Base Information

• Chemical Name: C₃₄H₅₈O₈Si₂
• CAS No.: 1012325-62-0
• Molecular Formula: C₃₄H₅₈O₈Si₂
• Molecular Weight: 651.001
• Mol file: 1012325-62-0.mol

Synonyms:C₃₄H₅₈O₈Si₂

Chemical Property of C₃₄H₅₈O₈Si₂

Chemical Property:

Purity/Quality:

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Technology Process of C₃₄H₅₈O₈Si₂

There total 1 articles about C₃₄H₅₈O₈Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(S)-pent-4-yn-2-yl 2-iodo-4,6-bis(methoxymethoxy)benzoate (1012325-59-5) + C18H41BO4Si2 → C34H58O8Si2 (1012325-62-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; thallium (I) ethoxide; In tetrahydrofuran; water; at 20 ℃; for 15.5h; Inert atmosphere;

DOI:10.1021/ol702961v

Reference yield: 66.0%

C34H58O8Si2 (1012325-62-0) → C22H30O8 + (S)-pent-4-yn-2-yl 2-((S,E)-5-(tert-butyldimethylsilyloxy)-6-hydroxyhex-1-enyl)-4,6-bis(methoxymethoxy)benzoate (1012325-74-4)

Guidance literature:

With pyridine hydrofluoride; In tetrahydrofuran; at -20 - 0 ℃; for 22h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol702961v

Reference yield:

chloro-trimethyl-silane (75-77-4) + C34H58O8Si2 (1012325-62-0) → (S)-5-(trimethylsilyl)pent-4-yn-2-yl 2-((S,E)-5,6-bis(tert-butyldimethylsilyloxy)hex-1-enyl)-4,6-bis(methoxymethoxy)benzoate (1012325-69-7)

Guidance literature:

C₃₄H₅₈O₈Si₂; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - -20 ℃; for 0.5h; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; at -78 - 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol702961v

upstream raw materials:

(S)-pent-4-yn-2-yl 2-iodo-4,6-bis(methoxymethoxy)benzoate

Downstream raw materials:

(S)-pent-4-yn-2-yl 2-((S,E)-5-(tert-butyldimethylsilyloxy)-6-hydroxyhex-1-enyl)-4,6-bis(methoxymethoxy)benzoate

(S)-5-(trimethylsilyl)pent-4-yn-2-yl 2-((S,E)-5,6-bis(tert-butyldimethylsilyloxy)hex-1-enyl)-4,6-bis(methoxymethoxy)benzoate