1,3-Dipalmitoyl-2-phosphatidylcholine

Base Information

Chemical Name:1,3-Dipalmitoyl-2-phosphatidylcholine
CAS No.:59540-22-6
Molecular Formula:C40H80 N O8 P
Molecular Weight:734.051
Hs Code.:
European Community (EC) Number:261-800-5
DSSTox Substance ID:DTXSID40208225
Mol file:59540-22-6.mol

Synonyms:1,3-DG-2-P;1,3-dipalmitoyl-2-phosphatidylcholine;1,3-dipalmitoyl-glycero-2-phosphocholine

Suppliers and Price of 1,3-Dipalmitoyl-2-phosphatidylcholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,3-DIHEXADECANOYL-GLYCERO-2-PHOSPHOCHOLINE 95.00%
5MG
$ 498.41

Total 4 raw suppliers

Chemical Property of 1,3-Dipalmitoyl-2-phosphatidylcholine

Chemical Property:

PSA：111.77000
LogP:12.09800
XLogP3:13.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:40
Exact Mass:733.56215551
Heavy Atom Count:50
Complexity:780

Purity/Quality:

99% ^*data from raw suppliers

1,3-DIHEXADECANOYL-GLYCERO-2-PHOSPHOCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OP(=O)([O-])OCC[N+](C)(C)C
Uses β-Dipalmitoyllecithin is a thermolabile liposome with controlled release temperature for use in drug delivery systems and labels.

Technology Process of 1,3-Dipalmitoyl-2-phosphatidylcholine

There total 10 articles about 1,3-Dipalmitoyl-2-phosphatidylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: hexadecanoic acid 2-[(2-bromo-ethoxy)-hydroxy-phosphoryloxy]-3-hexadecanoyloxy-propyl ester

: 75-50-3
trimethylamine

: 59540-22-6
1,3-di-O-hexadecanoyl-2-O-<<2-(trimethylamino)ethyl>phosphoryl>-rac-glycerol

Guidance literature:: In chloroform; water; isopropyl alcohol; acetonitrile; for 36h;
DOI:10.1055/s-0030-1258427

Reference yield:

: 502-52-3
hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester

: 59540-22-6
1,3-di-O-hexadecanoyl-2-O-<<2-(trimethylamino)ethyl>phosphoryl>-rac-glycerol

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / diethyl ether / 20 °C

1.2: H₂O / 1 h

2.1: CHCl₃; acetonitrile; propan-2-ol / 50 °C

With pyridine; In diethyl ether; chloroform; isopropyl alcohol; acetonitrile; 1.1: phosphorylation / 1.2: Hydrolysis / 2.1: Substitution;
DOI:10.1016/S0009-3084(99)00120-6