(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Base Information

Chemical Name:(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde
CAS No.:1225377-87-6
Molecular Formula:C₄₀H₄₈N₄O
Molecular Weight:600.847
Hs Code.:

(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Synonyms:(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Suppliers and Price of (5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

There total 23 articles about (5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1225377-86-5
(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-10′-(trimethylsilyl)-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

: 1225377-87-6
(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; 1,4-dioxane; at 101 ℃; for 10h; Inert atmosphere;
DOI:10.1021/ja101956x

Reference yield:

: 1225377-65-0
3-((1R,2S,4R,6S)-2-acetoxy-6-(cyanomethyl)-2-ethynyl-4-methylcyclohexyl)propyl acetate

: 1225377-87-6
(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Guidance literature:: Multi-step reaction with 7 steps

1: copper(l) chloride / tetrahydrofuran / 0.5 h / 80 °C / Inert atmosphere

2: potassium carbonate / methanol / 7 h / 23 °C / Inert atmosphere

3: triphenylphosphine; 1H-imidazole / tetrachloromethane / 15 h / 77 °C / Inert atmosphere

4: ammonium cerium (IV) nitrate / water; acetonitrile / 0.08 h / 23 °C / Inert atmosphere

5: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.5 h / 23 °C / Inert atmosphere

6: triphenylphosphine; dicarbonylcyclopentadienylcobalt / 1,4-dioxane / 24 h / 140 °C / Inert atmosphere

7: tetrabutyl ammonium fluoride / tetrahydrofuran; 1,4-dioxane / 10 h / 101 °C / Inert atmosphere

With 1H-imidazole; ammonium cerium (IV) nitrate; dicarbonylcyclopentadienylcobalt; tetrabutyl ammonium fluoride; potassium carbonate; N-ethyl-N,N-diisopropylamine; triphenylphosphine; copper(l) chloride; In tetrahydrofuran; 1,4-dioxane; methanol; tetrachloromethane; water; acetonitrile;
DOI:10.1021/jo400695c

Reference yield:

: 89-82-7,90449-51-7
pulegone

: 1225377-87-6
(5R,5′R,6S,6′S,14R,14′R,16R,16′R)-1-Benzyl-16,16′-dimethyl-1,2,2′,3,3′,4,4′,5,5′,6,6′,7,7′,15,16,16′,17,17′-octadecahydro[10,11′-bi(5,10b-propano1,7-phenanthroline)]-1′(15′H)-carbaldehyde

Guidance literature:: Multi-step reaction with 14 steps

1.1: lithium hydroxide; water / methanol / 23 °C / Inert atmosphere

2.1: sodium hydride / tetrahydrofuran / 66 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1.08 h / 0 °C / Inert atmosphere

3.2: 70 h / 23 °C / Inert atmosphere

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 11 h / -78 - 23 °C / Inert atmosphere

5.1: n-butyllithium / diethyl ether; hexane / 0.68 h / -78 °C / Inert atmosphere

5.2: 0.55 h / -78 °C / Inert atmosphere

6.1: tetrahydrofuran; toluene / 0.58 h / 23 °C / Inert atmosphere

7.1: magnesium(II) perchlorate / 0.5 h / 23 °C / Inert atmosphere

8.1: copper(l) chloride / tetrahydrofuran / 0.5 h / 80 °C / Inert atmosphere

9.1: potassium carbonate / methanol / 7 h / 23 °C / Inert atmosphere

10.1: triphenylphosphine; 1H-imidazole / tetrachloromethane / 15 h / 77 °C / Inert atmosphere

11.1: ammonium cerium (IV) nitrate / water; acetonitrile / 0.08 h / 23 °C / Inert atmosphere

12.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.5 h / 23 °C / Inert atmosphere

13.1: triphenylphosphine; dicarbonylcyclopentadienylcobalt / 1,4-dioxane / 24 h / 140 °C / Inert atmosphere

14.1: tetrabutyl ammonium fluoride / tetrahydrofuran; 1,4-dioxane / 10 h / 101 °C / Inert atmosphere

With 1H-imidazole; n-butyllithium; ammonium cerium (IV) nitrate; magnesium(II) perchlorate; dicarbonylcyclopentadienylcobalt; tetrabutyl ammonium fluoride; water; sodium hydride; potassium carbonate; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; copper(l) chloride; lithium hydroxide; In tetrahydrofuran; 1,4-dioxane; methanol; tetrachloromethane; diethyl ether; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; acetonitrile; mineral oil;
DOI:10.1021/jo400695c