2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

• Chemical Name: 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS No.: 1615227-20-7
• Molecular Formula: C₁₈H₂₉BO₃
• Molecular Weight: 304.237
• Mol file: 1615227-20-7.mol

Synonyms:2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 10 articles about 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-bromo-4-(4-methoxyphenyl)-2-methylbutane + bis(pinacol)diborane (73183-34-3) → 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1615227-20-7)

Guidance literature:

With manganese(II) bromide; N,N,N,N,-tetramethylethylenediamine; ethylmagnesium bromide; In 1,2-dimethoxyethane; diethyl ether; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jacs.6b03157

Reference yield: 81.0%

1-methoxy-4-(3-methylbut-3-en-1-yl)benzene (18491-21-9) + bis(pinacol)diborane (73183-34-3) → 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1615227-20-7)

Guidance literature:

With potassium tert-butylate; iron(II) chloride; In dimethyl sulfoxide; at 80 ℃; for 16h; Inert atmosphere; Schlenk technique;

Reference yield: 71.0%

3-chloro-1-(4-methoxyphenyl)-3-methylbutane (23020-47-5) + bis(pinacol)diborane (73183-34-3) → 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1615227-20-7)

Guidance literature:

With manganese(II) bromide; N,N,N,N,-tetramethylethylenediamine; ethylmagnesium bromide; In 1,2-dimethoxyethane; diethyl ether; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1021/jacs.6b03157

upstream raw materials:

3-hydroxy-1-(4-methoxyphenyl)-3-methylbutane

bis(pinacol)diborane

3-chloro-1-(4-methoxyphenyl)-3-methylbutane

(4-bromo-4-methylcyclohexyl)benzene