18491-21-9

Basic information

• Product Name: 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE
• Synonyms: 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE
• CAS NO: 18491-21-9
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25
• Mol File: 18491-21-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 246.064°C at 760 mmHg
• Flash Point: 92.234°C
• Appearance: /
• Density: 0.924g/cm³
• Vapor Pressure: 0.043mmHg at 25°C
• Refractive Index: 1.499
• CAS DataBase Reference: 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE(18491-21-9)
• EPA Substance Registry System: 4-(4-METHOXYPHENYL)-2-METHYL-1-BUTENE(18491-21-9)

Safety Data

• Hazardous Substances Data: 18491-21-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O/c1-10(2)4-5-11-6-8-12(13-3)9-7-11/h6-9H,1,4-5H2,2-3H3

Upstream product

• 104-20-1 4-(4-methoxyphenyl)-2-butanone 
• 19493-09-5 Methylenetriphenylphosphorane 
• 100-66-3 methoxybenzene 
• 556-82-1 3-methyl-2-buten-1-ol 
• 943-88-4 4-(p-methoxyphenyl)-3-butene-2-one 
• 123-11-5 4-methoxy-benzaldehyde 
• 14425-64-0 4-methoxyphenethyl bromide 
• 131161-70-1 1-(2-cyclopropylethyl)-4-methoxybenzene 
• 18292-38-1 2-methallyltrimethylsilane 
• 104-21-2 p-methoxybenzyl acetate 
• 1822-00-0 trimethylsilylmethyllithium 
• 290309-44-3 4-(p-Methoxyphenyl)-2-butanone ethylene acetal 
• 122948-45-2 4-(p-Methoxyphenyl)-2-butanone dimethyl acetal 
• 75-89-8 2,2,2-trifluoroethanol 

Downstream Products

• 4957-18-0 1-methoxy-4-(3-methyl-but-2-enyl)benzene 
• 14305-29-4 3-hydroxy-1-(4-methoxyphenyl)-3-methylbutane 
• 184779-69-9 1-Methoxy-4-[3-methyl-3-(2,2,2-trifluoro-ethoxy)-butyl]-benzene 
• 1615227-20-7 2-(4-(4-methoxyphenyl)-2-methylbutan-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

Mechanistic imperatives for the reaction catalyzed by isopentenyl pyrophosphate isomerase: Free energy profile for stepwise isomerization in water through a tertiary carbocation intermediate

Rate and equilibrium constants are reported for the stepwise allylic 1,3-isomerization of 4-(4-methoxyphenyl)-2-methyl-1-butene (2) to give 4-(4-methoxyphenyl)-2-methyl-2-butene (3) in water through a simple tertiary carbocation intermediate 1+

Synthesis of α-Tertiary Amine Derivatives by Intermolecular Hydroamination of Unfunctionalized Alkenes with Sulfamates under Trifluoromethanesulfonic Acid Catalysis

An efficient and mild trifluoromethanesulfonic acid-catalyzed hydroamination of unfunctionalized alkenes to afford α-tertiary amine derivatives at temperatures as low as room temperature is reported. 2,2,2-Trifluoroethyl sulfamate was found to be the optimal nitrogen source because its good solubility in both organic solvents and water facilitated both conversion and purification. The reaction conditions were compatible with a variety of substrate functional groups and afforded moderate to good yields. The desired amine compounds could be obtained easily by means of a mild, one-pot, redox-neutral deprotection procedure. Caryolane amine was synthesized with excellent chemo- and regioselectivities by means of a cascade hydroamination reaction of β-caryophyllene.

Rhodium-catalyzed allylation of benzyl acetates with allylsilanes

Benzyl acetate reacted with allyltrimethylsilane to give an allylation product in the presence of a catalytic amount of the (cyclooctadiene)rhodium(I) chloride dimer {[Rh(cod)Cl]2}, sodium tetrakis[3,5- bis(trifluoromethyl)phenyl]borate (NaBARF), and triphenyl phosphite [P(OPh) 3] in refluxing 1,2-dichloroethane. Primary, secondary and tertiary benzyl acetates could be used for the reaction. Moreover, allylation of gem-benzyl acetate was possible with [Rh(cod)Cl]2, NaBARF, and P(OPh)3. Monoallylation and diallylation of gem-benzyl acetate could be controlled by altering the reaction conditions. Cationic rhodium species generated in situ act as a Lewis acid catalyst to give a benzyl carbocation by elimination of the acetoxy group from the benzylic carbon. Copyright