4-methoxy-N-(3-pentyl)aniline

Base Information

• Chemical Name: 4-methoxy-N-(3-pentyl)aniline
• CAS No.: 857591-32-3
• Molecular Formula: C₁₂H₁₉NO
• Molecular Weight: 193.289
• Mol file: 857591-32-3.mol

Synonyms:4-methoxy-N-(3-pentyl)aniline

Chemical Property of 4-methoxy-N-(3-pentyl)aniline

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-methoxy-N-(3-pentyl)aniline

There total 7 articles about 4-methoxy-N-(3-pentyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

ethene (74-85-1) + N-methyl-N-(4-methoxyphenyl)amine (5961-59-1) → N-(4-methoxyphenyl)-N-propylamine (71193-47-0) + 4-methoxy-N-(3-pentyl)aniline (857591-32-3)

Guidance literature:

With C₃₁H₅₃N₅Ti; In toluene; at 160 ℃; for 24h; under 1064.07 Torr; Schlenk technique; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1002/chem.201904502

Reference yield: 89.0%

C12H17NO (781628-30-6) → 4-methoxy-N-(3-pentyl)aniline (857591-32-3)

Guidance literature:

With phenylsilane; C₁₂H₃₇CoP₄⁽¹⁺⁾; In toluene; at 110 ℃; for 1h;

DOI:10.1021/acscatal.1c03886

Reference yield: 53.0%

2-pentanol (584-02-1) + 4-methoxy-aniline (104-94-9) → 4-methoxy-N-(3-pentyl)aniline (857591-32-3)

Guidance literature:

With trimethylamine-N-oxide; [bis(hexamethylene)cyclopentadienone]iron tricarbonyl; In toluene; at 150 ℃; for 72h; Time; Inert atmosphere; Schlenk technique; Molecular sieve; Sealed tube;

DOI:10.1055/s-0039-1690101

upstream raw materials:

(E)-4-methoxybenzaldoxime

ethylmagnesium bromide

4-methoxy-benzaldehyde-(O-carbamoyl oxime )

4-methoxyformanilide

Refernces

• 1、 Rosien, Michael,T?ben, Iris,Schmidtmann, Marc,Beckhaus, Rüdiger,Doye, Sven. "Titanium-Catalyzed Hydroaminoalkylation of Ethylene". supporting information. p. 2138 - 2142. Retrieved 2020/02/05.
• 2、 Bhunia, Mrinal,Hota, Pradip Kumar,Vijaykumar, Gonela,Adhikari, Debashis,Mandal, Swadhin K.. "A Highly Efficient Base-Metal Catalyst: Chemoselective Reduction of Imines to Amines Using An Abnormal-NHC-Fe(0) Complex". supporting information. p. 2930 - 2937. Retrieved 2016/10/06.