2-METHYL-5-ISOPROPYLANILINE

Base Information

• Chemical Name: 2-METHYL-5-ISOPROPYLANILINE
• CAS No.: 2051-53-8
• Molecular Formula: C10H15 N
• Molecular Weight: 149.236
• Hs Code.: 2921490090
• Mol file: 2051-53-8.mol

Synonyms:Carvacrylamine(6CI,7CI,8CI); 2-Amino-p-cymene; 2-Cymidine; 2-Methyl-5-isopropylaniline;3-Isopropyl-6-methylphenylamine; 5-Isopropyl-2-methylaniline;5-Isopropyl-2-methylphenylamine; 5-Isopropyl-o-toluidine;6-Methyl-3-isopropylaniline; NSC 4021; p-Cymen-2-amine

Chemical Property of 2-METHYL-5-ISOPROPYLANILINE

Chemical Property:

• Vapor Pressure: 0.0356mmHg at 25°C
• Melting Point: -16°C
• Refractive Index: 1.5380 to 1.5420
• Boiling Point: 385.7°Cat760mmHg
• PKA: 4.53±0.10(Predicted)
• Flash Point: 187.1°C
• PSA: 26.02000
• Density: 1.18g/cm³
• LogP: 3.28180
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methyl-5-isopropylaniline ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-5-ISOPROPYLANILINE

There total 32 articles about 2-METHYL-5-ISOPROPYLANILINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-nitro-p-cymene (943-15-7) → 5-isopropyl-2-methylphenylamine (2051-53-8) + trans-2,2'-Azo-p-cymene (51556-93-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/je00030a030

Reference yield: 50.0%

carvacrol (499-75-2) → 5-isopropyl-2-methylphenylamine (2051-53-8)

Guidance literature:

With sodium tetrahydroborate; 5%-palladium/activated carbon; hydrazine hydrate; In 1,4-dioxane; at 170 ℃; for 16h; Molecular sieve; Inert atmosphere;

DOI:10.1039/c9sc00595a

Reference yield:

sulfuric acid (7664-93-9) + carvoxime (31198-76-2) → carvacrol (499-75-2) + 5-isopropyl-2-methylphenylamine (2051-53-8)

Guidance literature:

d-carvoxime;

upstream raw materials:

carbonyl azide

4-methylisopropylbenzene

carvacrol

p-mentha-4⁽⁸⁾,6-dien-2-one oxime

Downstream raw materials:

5-isopropyl-2,N,N-trimethyl-aniline

N,N-diethyl-N'-(5-isopropyl-2-methyl-phenyl)-ethylenediamine

2-chloro-N-[2-methyl-5-(propan-2-yl)phenyl]acetamide

2-chloro-propionic acid-(5-isopropyl-2-methyl-anilide)

Refernces

• 1、 Kovacic,Hopper. "". . p. 3965,3975. Retrieved 1967.
• 2、 Tyler, Jefferson H.,Nazari, S. Hadi,Patterson, Robert H.,Udumula, Venkatareddy,Smith, Stacey J.,Michaelis, David J.. "Synthesis of N-aryl and N-heteroaryl hydroxylamines via partial reduction of nitroarenes with soluble nanoparticle catalysts". . p. 82 - 86. Retrieved 2016/12/23.