1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione

Base Information

• Chemical Name: 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione
• CAS No.: 1430799-23-7
• Molecular Formula: C₁₄H₁₄N₄O₂
• Molecular Weight: 270.291
• Mol file: 1430799-23-7.mol

Synonyms:1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione

Chemical Property of 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione

There total 2 articles about 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-(prop-2-yn-1-yl)pyrrolidine-2,5-dione (10478-33-8) + benzyl azide (622-79-7) → 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione (1430799-23-7)

Guidance literature:

With [(1-phenylisoquinoline)₂Ir(acetylacetonate)]; In dichloromethane; at 20 ℃; regioselective reaction; Irradiation;

DOI:10.1002/chem.202000252

Reference yield:

benzyl bromide (100-39-0) → 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione (1430799-23-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 40 °C

2: [(1-phenylisoquinoline)₂Ir(acetylacetonate)] / dichloromethane / 20 °C / Irradiation

With sodium azide; [(1-phenylisoquinoline)₂Ir(acetylacetonate)]; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.202000252

Reference yield: 76.0%

1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)pyrrolidine-2,5-dione (1430799-23-7) + toluene-4-sulfonic acid (104-15-4) → C14H14N4O2*C7H8O3S (1605323-46-3)

Guidance literature:

at 60 ℃; for 72h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejoc.201301220

upstream raw materials:

1-(prop-2-yn-1-yl)pyrrolidine-2,5-dione

benzyl azide

benzyl bromide

Downstream raw materials:

C₁₄H₁₄N₄O₂*C₇H₈O₃S