benzhydrylacetamide-d₃

Base Information

• Chemical Name: benzhydrylacetamide-d₃
• CAS No.: 1325231-85-3
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 228.266
• Mol file: 1325231-85-3.mol

Synonyms:benzhydrylacetamide-d₃

Chemical Property of benzhydrylacetamide-d₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzhydrylacetamide-d₃

There total 3 articles about benzhydrylacetamide-d₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[D3]acetonitrile (2206-26-0) + Bromodiphenylmethane (776-74-9) → benzhydrylacetamide-d3 (1325231-85-3)

Guidance literature:

With pyridine; 2CF₃O₃S^(1-)*C₁₂H₁₀I₄N₄⁽²⁺⁾; cyclohexene; In water; for 48h; Inert atmosphere;

DOI:10.1039/c2cc34392d

Reference yield: 86.0%

[D3]acetonitrile (2206-26-0) + diphenylchloromethane (90-99-3) → benzhydrylacetamide-d3 (1325231-85-3)

Guidance literature:

With C₁₄H₁₅OTe⁽¹⁺⁾*CF₃O₃S^(1-); In water; at 25 ℃; for 96h;

DOI:10.1039/d1cc06311a

Reference yield:

[D3]acetonitrile (2206-26-0) + Bromodiphenylmethane (776-74-9) → 1,1-Diphenylmethanol (91-01-0) + benzhydryl ether (574-42-5) + benzhydrylacetamide-d3 (1325231-85-3)

Guidance literature:

With pyridine; (E)-1-methyl-3,5-diiodo-4-(1-methylpyridinium-4-yldiazenyl)pyridinium bis(trifluoromethanesulfonate); water; cyclohexene; at 20 ℃; for 36h;

DOI:10.1002/chem.201103071

upstream raw materials:

[D₃]acetonitrile

Bromodiphenylmethane

diphenylchloromethane

Refernces

• 1、 Yang, Mengxi,Tofan, Daniel,Chen, Chang-Hong,Jack, Kevin M.,Gabba?, Fran?ois P.. "Digging the Sigma-Hole of Organoantimony Lewis Acids by Oxidation". . p. 13868 - 13872. Retrieved 2018.
• 2、 Wonner, Patrick,Vogel, Lukas,Düser, Maximilian,Gomes, Luís,Kniep, Florian,Mallick, Bert,Werz, Daniel B.,Huber, Stefan M.. "Carbon–Halogen Bond Activation by Selenium-Based Chalcogen Bonding". . p. 12009 - 12012. Retrieved 2017.
• 3、 Benz, Sebastian,Besnard, Celine,Matile, Stefan. "Chalcogen-Bonding Catalysis: From Neutral to Cationic Benzodiselenazole Scaffolds". . . Retrieved 2018.
• 4、 Kikkawa, Shoko,Sakakibara, Nao,Takagi, Koji,Tsuzuki, Seiji. "Dicationic oligotelluroxane or mononuclear telluronium cation? Elucidation of the true catalytic species and activation mechanism of the benzylic carbon-halogen bond". supporting information. p. 13736 - 13739. Retrieved 2021/12/27.
• 5、 Voelkel, Martin H. H.,Wonner, Patrick,Huber, Stefan Matthias. "Preorganization: A Powerful Tool in Intermolecular Halogen Bonding in Solution". . p. 214 - 224. Retrieved 2020/03/10.