Technology Process of isopropyl 2-(benzyloxy)-8-(tert-butyldimethylsilyloxy)octanoate
There total 6 articles about isopropyl 2-(benzyloxy)-8-(tert-butyldimethylsilyloxy)octanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium iodide; silver(l) oxide;
In
dichloromethane;
at 20 ℃;
for 9h;
Inert atmosphere;
DOI:10.1016/j.bmcl.2011.12.025
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium cyanoborohydride / isopropyl alcohol / 43 h / 70 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: potassium iodide; silver(l) oxide / dichloromethane / 9 h / 20 °C / Inert atmosphere
With
sodium cyanoborohydride; potassium iodide; silver(l) oxide;
In
dichloromethane; isopropyl alcohol;
DOI:10.1016/j.bmcl.2011.12.025
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1H-imidazole / tetrahydrofuran; dichloromethane / 26 h / 0 - 20 °C / Inert atmosphere
2.1: Dess-Martin periodane / dichloromethane / 3.25 h / 20 °C / Inert atmosphere
3.1: potassium isopropoxide / diethyl ether; isopropyl alcohol / 0.17 h / 0 °C / Inert atmosphere
3.2: 1.67 h / 0 °C / Inert atmosphere
4.1: sodium cyanoborohydride / isopropyl alcohol / 43 h / 70 °C / Inert atmosphere
4.2: Inert atmosphere
5.1: potassium iodide; silver(l) oxide / dichloromethane / 9 h / 20 °C / Inert atmosphere
With
1H-imidazole; potassium isopropoxide; sodium cyanoborohydride; Dess-Martin periodane; potassium iodide; silver(l) oxide;
In
tetrahydrofuran; diethyl ether; dichloromethane; isopropyl alcohol;
3.2: Darzens condensation;
DOI:10.1016/j.bmcl.2011.12.025
