Sulfur Hexafluoride

Base Information

• Chemical Name: Sulfur Hexafluoride
• CAS No.: 2551-62-4
• Deprecated CAS: 29267-82-1,36575-03-8,59109-69-2,36575-03-8
• Molecular Formula: S F6
• Molecular Weight: 146.056
• Hs Code.: 2812901990
• UN Number: 1080
• UNII: WS7LR3I1D6
• DSSTox Substance ID: DTXSID8029656
• Nikkaji Number: J95.218D
• Wikipedia: Sulfur hexafluoride
• Wikidata: Q279055
• NCI Thesaurus Code: C84187
• RXCUI: 1599276
• ChEMBL ID: CHEMBL1796998
• Mol file: 2551-62-4.mol

Synonyms:Hexafluoride, Sulfur;Sulfur Hexafluoride

Chemical Property of Sulfur Hexafluoride

Chemical Property:

• Appearance/Colour: colourless odourless gas
• Vapor Pressure: 22 mm Hg ( 21.1 °C)
• Melting Point: ?50°C(lit.)
• Boiling Point: -64 °C (subl.)
• PSA: 25.30000
• Density: 6.602
• LogP: 3.16940
• Water Solubility.: slightly
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 145.96249015
• Heavy Atom Count: 7
• Complexity: 62.7
• Transport DOT Label: Non-Flammable Gas

Purity/Quality:

99.0% ^*data from raw suppliers

Sulfur hexafluoride 99.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 37
• Safety Statements: 38

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Toxic Gases & Vapors -> Simple Asphyxiants
• Canonical SMILES: FS(F)(F)(F)(F)F
• Recent ClinicalTrials: Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDH
• Recent EU Clinical Trials: Vastasyntyneen aivojen kontrastiultra??ni- ja elastografiatutkimus
• Uses: ▼▲ Industry Application Role/benefit Medicine Anesthesia Anesthetic/better anesthesia effect than nitric oxide Retinal detachment repair operations Provide a tamponade or plug of a retinal hole in the form of a gas bubble Ultrasound imaging Contrast agent/enhance the visibility of blood vessels to ultrasound Semiconductor Plasma etching Etchant/breaking down product fluorine plasma can perform the etching Metal casting Magnesium and aluminum casting Oxygen asphyxiant/inert and not corrosive and toxic High-power microwave systems Pressurizes waveguides Insulates the waveguide, preventing internal arcing Chemical weapon Production of disulfur decafluoride Feedstock Magic show Object floating show Be colorless, tasteless and has greater density than air Electrical equipment High-voltage circuit breakers and gas insulated switchgear Gaseous dielectric medium/has much higher dielectric strength than air or dry nitrogen Others Tennis, insoles filling Gas filler/much lower capacity to pass through rubber membrane than air Monitor the flow of the water and the diffusion of the air pollutants Tracer agent/ stably exists in water and air Zanyism Performers breathe a little sulfur hexafluoride gas to make the voice become low and deep Refrigerant Good chemical stability and no corrosion on the equipment Sulfur hexafluoride is used extensively as a gaseous dielectric in various kinds of electrical power equipment, such as switchgear, transformers, condensers, and circuit breakers. It has also been used as a dielectric at microwave frequencies and as an insulating medium for the power supplies of high-voltage machines. Sulfur hexafluoride is also gaining use in nonelectrical applications, including blanketing of molten magnesium, leak detection, and plasma etching in the semiconductor industry. Sulfur hexafluoride also has some limited medical applications. Dielectric for high-voltage equipment Sulfur hexafluoride is used extensively as a gaseous dielectric in various kinds of electrical power equipment, such as switchgear, transformers, condensers, and circuit breakers. It has also been used as a dielectric at microwave frequencies and as an insulating medium for the power supplies of high-voltage machines. Sulfur hexafluoride is also gaining use in nonelectrical applications, including blanketing of molten magnesium, leak detection, and plasma etching in the semiconductor industry. Sulfur hexafluoride also has some limited medical applications.
• Description: Sulfur hexafluoride is a colorless, odorless, nontoxic, nonflammable gas that has a high dielectric strength and serves widely as an insulating gas in electrical equipment. At atmospheric pressures it sublimes directly from the solid to the gas phase and does not have a stable liquid phase unless under a pressure of more than 32 psia (221 kPa, abs). It is shipped as a liquefied compressed gas at its vapor pressure of 298 psig at 70°F (2050 kPa at 21.1°C). One of the most chemically inert gases known, it is completely stable in the presence of most materials to temperatures of about 400°F (204°C) and has shown no breakdown or reaction in quartz at 900°F (482°C). Sulfur hexafluoride is slightly soluble in water and oil. No change in pH occurs when distilled water is saturated with sulfur hexafluoride.
• Physical properties: Colorless, odorless gas; density 6.41 g/L; about five times heavier than air; liquefies at -50.7°C (triple point); density of liquid 1.88 g/mL at -50.7°C; sublimes at -63.8°C; critical temperature 45.54°C; critical pressure 37.13 atm; critical volume 199 cm3/mol; slightly soluble in water; soluble in ethanol.

Technology Process of Sulfur Hexafluoride

There total 106 articles about Sulfur Hexafluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

fluorine (7782-41-4) + sulfur (7704-34-9) → disulfur decafluoride (5714-22-7) + disulfur difluoride (13709-35-8) + sulfur tetrafluoride (7783-60-0) + hydrogen fluoride (7664-39-3,12381-92-9,32057-09-3,74835-82-8) + sulfur(VI) hexafluoride (2551-62-4)

Guidance literature:

In neat (no solvent); byproducts: OF2; introduction of F2 into steel chamber, sulfur in compartments; detailed description of apparatus and handling given;; first passing through Ni (or Monel) tube (400°C); second Cu column (H2O sprayed); passed into steel column (containing carbon/Fe shavings; aq. NaOH sprayed); dried in column (containing solid NaOH, BaO or P2O5);;

Reference yield: 5.0%

thiocyanogen (505-14-6) + fluorine (7782-41-4) → thiazyl trifluoride (15930-75-3) + sulphur cyanide pentafluoride (1512-13-6) + sulfur tetrafluoride (7783-60-0) + thionyl fluoride (7783-42-8) + sulfur(VI) hexafluoride (2551-62-4)

Guidance literature:

In further solvent(s); byproducts: (FCN)3; reactn. of a soln. of dirhodane in FCl2C-CClF2 with diluted F2 (F2:N2 0 1:10); cooled down to -183°C; solvent removed by condensation; mixt. condensed to aq. KOH-soln. at room temp. to remove SF4, SOF and (FCN)3; sepn. by fractionated condensation at -127°C, -140°C, -196°C;

Reference yield:

silver(II) fluoride → thiazyl trifluoride (15930-75-3) + thiazyl fluoride tetramer (13840-72-7) + thiazyl fluoride (18820-63-8) + sulfur tetrafluoride (7783-60-0) + sulfur(VI) hexafluoride (2551-62-4)

Guidance literature:

With ammonia; sulfur; In tetrachloromethane; passing NH3 through a suspension of AgFs and S in CCl4; further products;;

upstream raw materials:

nitrosylchloride

pentafluorosulfur hypofluorite

sulfur dioxide

hydrogen fluoride

Downstream raw materials:

fluorosulfonyl fluoride

sulfur tetrafluoride

thionyl fluoride

lead monofluoride

Refernces

Use of SF₆ for the production of electrophilic ¹⁸F-fluorination reagents

10.1016/j.jfluchem.2017.10.010

The research investigates a novel method for producing electrophilic 18F-fluorination reagents without using toxic F2 gas. The study explores the use of SF6 as an alternative, testing its efficacy in two different matrix gases, Ne and Xe. The results show that SF6 in Xe can effectively produce electrophilic [18F]F2 gas, which was successfully used to label model compounds like 6-[18F]fluoro-L-DOPA and [18F]Selectfluor bis(triflate). In contrast, using SF6 in Ne resulted in only trace amounts of [18F]F2. Spectrometric analysis revealed that atomic fluorine was not detected during discharge in Xe, suggesting the formation of excited Xe-F* intermediate species. The study concludes that SF6 in Xe is a viable alternative for producing electrophilic 18F-fluorination reagents, offering a safer and more practical method for PET tracer production. Future work should focus on optimizing the yield and molar activity of the reagents produced.